Quinazoline - Wikipedia
Quinazoline is an organic compound with the formula C 8 H 6 N 2. It is an aromatic heterocycle with a bicyclic structure consisting of two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring. It is a light yellow crystalline solid that is soluble in water.
An overview of quinazolines: Pharmacological significance and …
2018年5月10日 · Quinazoline (1,3-diazanaphthalene) is a nitrogen containing heterocyclic compound illustrated by a double-ring structure that contains a benzene ring system fused to pyrimidine at two adjacent carbon atoms (Fig. 1).
An overview of quinazolines: Pharmacological significance and recent ...
2018年5月10日 · This review gives detailed attention on in vitro and in vivo pharmacological activities of quinazoline and its analogs in the perspective of drug discovery and its development.
Chemical Insights Into the Synthetic Chemistry of Quinazolines: …
Quinazoline (1,3-diazanaphthalene; 1) is a moiety made up of two condensed six-membered aromatic rings, a pyrimidine ring, and a benzene ring (Wang and Gao, 2013). It is yellow and amorphous, and its molar mass is 130.15 g.mol −1, and the chemical formula is C 8 H 6 N 2.
Chemical Characteristics, Synthetic Methods, and Biological …
Quinazolines and quinazolinone are a large class of biologically active compounds that exhibited broad spectrum of biological activities such as anti-HIV, anticancer, antifungal, antibacterial, antimutagenic, anticoccidial, anticonvulsant, anti-inflammatory, antidepressant, antimalarial, antioxidant, antileukemic, and antileishmanial activities ...
Quinazoline | C8H6N2 | CID 9210 - PubChem
Quinazoline is a mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms. It is a mancude organic heterobicyclic parent, a member of quinazolines, an azaarene and an ortho-fused heteroarene.
An insight into the therapeutic potential of quinazoline …
In recent years, quinazoline and its derivatives have been considered as a novel class of cancer chemotherapeutic agents that show promising activity against different tumors.
Quinazoline - an overview | ScienceDirect Topics
Quinazoline is a bicyclic heterocycle with benzene ring fused with pyrimidine nucleus. Quinazoline has contributed to many pharmacological profiles such as anti-cancer, anti inflammatory [58], anti-tubercular [59], antibacterial [60], anti leishmanial agents [61].
Advances in synthesis and biological activities of quinazoline …
2023年10月1日 · Quinazoline, a heterocyclic compound with nitrogen, is one of the most significant heterocyclic motifs with diverse chemical reactivities and many biological applications. Its derivatives comprise a family of fused heterocycles in over 200 naturally occurring alkaloids.
Medicinal Chemistry of Quinazolines as Analgesic and Anti ... - MDPI
2022年12月2日 · The developing understanding of quinazoline derivatives and their biological targets presents opportunities for the discovery of novel therapeutics. This review represents different aspects of medicinal chemistry, including drug design, structure–activity relationship, and the mode of action of some analgesic and anti-inflammatory quinazoline ...