Pyrimidine dimer - Wikipedia
Cyclobutane pyrimidine dimer (CPD) is a dimer which features a four-membered ring formed by the fusion of two double-bonded carbons from adjacent pyrimidines. CPDs disrupt the formation of the base pair during DNA replication , potentially leading to mutations .
Pyrimidine Dimer - an overview | ScienceDirect Topics
Thymine dimers occur when DNA is exposed to UV radiation. The most common form, cis-syn cyclobutane pyrimidine dimer (CPD), is a strong block to replicative DNA polymerases.
DNA Repair - The Cell - NCBI Bookshelf
Examples of DNA damage induced by radiation and chemicals. (A) UV light induces the formation of pyrimidine dimers, in which two adjacent pyrimidines (e.g., thymines) are joined by a cyclobutane ring structure. (B) Alkylation is the addition of methyl
Pyrimidine Dimer - an overview | ScienceDirect Topics
A pyrimidine dimer is an intrastrand DNA cross-link caused by exposure to ultraviolet light, which can block DNA replication and transcription. Various DNA repair mechanisms exist to remove pyrimidine dimers, as defects in their removal can lead to diseases and cancer in humans.
嘧啶二聚体 - 维基百科，自由的百科全书
嘧啶二聚体（pyrimidine dimer，简称PD），是DNA或RNA中的相邻碱基，如胞嘧啶及胸腺嘧啶，在紫外线的诱导下進行光化学合成，於碳-碳雙鍵生成共价键而形成的一种化合物，是突变产生的原因之一。
Pyrimidine Dimer - an overview | ScienceDirect Topics
Pyrimidine dimers are structures that form between two of four nucleotide bases that make up DNA: the nucleotides cytosine and thymine, which are members of the chemical family called pyrimidines. From: Animal Biotechnology, 2014
9.3: DNA Repair - Biology LibreTexts
2. Pyrimidine Dimerization. UV light exposure of DNA can cause adjacent pyrimidines (commonly thymines; less often, cytosines) on a DNA strand to dimerize. Pyrimidine dimers form at a rate of a bit less than 100 per cell per day! Uncorrected dimerization results in 2-base deletion in one chromosome while the other is unchanged (below).
嘧啶二聚體 - 維基百科，自由的百科全書
嘧啶二聚體（pyrimidine dimer，簡稱PD），是DNA或RNA中的相鄰鹼基，如胞嘧啶及胸腺嘧啶，在紫外線的誘導下進行光化學合成，於碳-碳雙鍵生成共價鍵而形成的一種化合物，是突變產生的原因之一。
Pyrimidine dimer | C8H8N4 | CID 22057568 - PubChem
2021年10月14日 · Pyrimidine Dimer is a pair of pyrimidine bases (thymine or cytosine in DNA or uracil in double-stranded RNA) within a nucleic acid covalently linked by a cyclobutane ring, the formation of which was induced by exposure to ultraviolet radiation.
Molecular Mechanisms of Ultraviolet Radiation-Induced DNA …
Ultraviolet radiation (UVR) (mainly UV-B: 280–315 nm) is one of the powerful agents that can alter the normal state of life by inducing a variety of mutagenic and cytotoxic DNA lesions such as cyclobutane-pyrimidine dimers (CPDs), 6-4 photoproducts (6-4PPs), and their Dewar valence isomers as well as DNA strand breaks by interfering the ...