2-Pyridone catalyses a variety of proton-dependent reactions, for example the aminolysis of esters. In some cases, molten 2-pyridone is used as a solvent. 2-Pyridone has a large effect on the reaction from activated esters with amines in nonpolar solvent , which is attributed to its tautomerisation and utility as a ditopic receptor.

Pyridone may refer to several organic compounds with the formula C 5 H 4 NH(O): 2-Pyridone; 3-hydroxypyridine; 4-Pyridone; These can adopt three tautomers, a oxo form, a zwitterion form, and a enol form.

A pyridone is an ambidentate ligand that forms d-f complexes in different oligomeric forms depending on the type of pyridone ligand, the starting d-complex, the anion present, and the solvent used. AI generated definition based on: Coordination Chemistry Reviews, 2001

2021年4月15日 · Pyridones are a unique class of heterocycles, possessing both a carbonyl group and a nitrogen heteroatom in a 6-membered aromatic ring. Depending on the location of the nitrogen atom with respect to the carbonyl moiety, two types of pyridones are known: 2-pyridones and 4-pyridones as depicted in Fig. 1 a.

2021年4月15日 · Pyridones have been utilized as privileged scaffolds in drug discovery.

2021年6月1日 · The chemistry and applications of 2-pyridone structures have recently attracted a lot of attention due to their uses as synthetic intermediates and their biological importance. Furthermore, 2-pyridones are a different category of pharmacophores that exhibit several biological activities.

4-Pyridone is an organic compound with the formula C 5 H 4 NH(O). It is a colorless solid.

Explore the intriguing world of pyridones, their structure, synthesis, unique properties, and diverse applications in our comprehensive guide. The term ‘Pyridone’ refers to a class of organic compounds structurally related to the heterocyclic compound pyridine.

As catabolites of nicotinamide possess physiological relevance, pyridones are often included in metabolomics measurements and associated with pathological outcomes in acute kidney injury (AKI). Pyridones are oxidation products of nicotinamide, its …

Thus, the selective synthesis of substituted 2-pyridone derivatives through decoration and/or formation of pyridone rings has been one of the important longstanding subjects in organic synthetic chemistry. This minireview focuses on recent advances in site-selective C–H functionalization on 2-pyridone.