2024年12月25日 · PYCARD (PYD And CARD Domain Containing) is a Protein Coding gene. Diseases associated with PYCARD include Muckle-Wells Syndrome and Familial …

PYCARD, known as apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), was firstly found to be related to apoptosis of human promyelocytic leukemia …

2022年10月12日 · PYCARD is a protein engaged in inflammation, pyroptosis, and apoptosis. However, the function of PYCARD in human cancers remains unclear. The objective of our …

2025年1月5日 · This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal …

2019年4月29日 · The NLRP3 inflammasome consists of a sensor (NLRP3), an adaptor (ASC; also known as PYCARD) and an effector (caspase 1).

2011年2月3日 · ASC, also called PYCARD /TMS1, is a bipartite protein that consists of a pyrin domain and a caspase recruitment domain (CARD) domain motif [188]. ASC is expressed in …

PYCARD, also known as ASC (Apoptosis-associated speck-like protein containing a CARD), plays a crucial role in both apoptosis and inflammation. It promotes caspase-mediated …

PYCARD serves as an adaptor protein with pivotal roles in assembling inflammatory responses and regulating cell apoptosis. Its functionality as an adaptor molecule is attributed to its …

2024年4月24日 · PYCARD was a critical PANoptosis-related gene in all COPD patients. PYCARD was positively related to NOD-like receptor signaling pathway and promoted immune cell …

2025年1月5日 · This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal …