Can sunlight be used for PUVA? Where PUVA cabinets are unavailable, some dermatologists have recommended patients are exposed to sunlight after taking psoralens by mouth or applying psoralens topically. The oral psoralen has usually been trisoralen as this is …

The efficacy of oral psoralen + sun exposure (PUVAsol) is comparable to that of PUVA. This study was planned to compare the efficacy of oral PUVAsol with that of the combination of oral isotretinoin and PUVAsol in patients with chronic plaque psoriasis. Methods: Forty patients with psoriasis vulgaris were randomized to two groups.

2024年9月6日 · Psoralen combined with long-wave ultraviolet radiation (PUVA light therapy) is used to treat many different chronic skin conditions, including psoriasis. Psoralen can be taken orally or administered topically. It makes the skin more sensitive to UVA light, which allows deep penetration of light to the skin.

Psoralens are initially biologically inert and acquire photoreactivity when exposed to certain classes of electromagnetic radiation, such as ultraviolet light. Once activated, psoralens form mono- and di-adducts with DNA, leading to marked cell apoptosis.

2007年8月16日 · Psoralens and exposure to sunlight have been used for thousands of years to treat vitiligo and induce pigmentation.

2025年1月23日 · UVB is present in natural sunlight and is an effective treatment for psoriasis. UVB penetrates the skin and slows the growth of affected skin cells. Treatment using UVB can include UVB phototherapy, excimer laser, or in-office or home UVB phototherapy.

2014年5月15日 · The efficacy of oral psoralen + sun exposure (PUVAsol) is comparable to that of PUVA. This study was planned to compare the efficacy of oral PUVAsol with that of the combination of oral isotretinoin and PUVAsol in patients with chronic plaque psoriasis. Forty patients with psoriasis vulgaris were randomized to two groups.

2021年8月11日 · For centuries, Psoralen, along with natural sunlight, has been used by medical experts to increase the penetration of ultraviolet light into the skin, thereby preventing some skin conditions. It is found that the compound works by making the skin more sensitive to …

2024年3月12日 · Today, doctors use psoralens with sunlamps or light booths that emit ultraviolet light. This is called PUVA or photochemotherapy. How Do You Take Psoralens? Psoralens usually come in capsules...

We have given you this factsheet because your dermatology (skin) doctor has referred you for a course of psoralen ultraviolet light A (PUVA) treatment. It explains what PUVA treatment is, how to prepare for it and the risks and benefits of the treatment. We hope it …