Dec 25, 2024 · PSMD4 (Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 4) is a Protein Coding gene. Diseases associated with PSMD4 include Cholera and Alzheimer's Disease. …

In brief, 20S sub complex presents three types proteolytic activities, including caspase-like, trypsin-like, and chymotrypsin-like activities. These proteolytic active sites located in the inner …

PSMD4 drives progression of hepatocellular carcinoma via Akt/COX2 pathway and p53 inhibition. Upregulation of Rpn10 promotes tumor progression via activation of the NF-kappaB pathway …

May 25, 2023 · PSMD4/Rpn10 is a subunit of the 19S proteasome unit that is involved with feeding target proteins into the catalytic machinery of the 26S proteasome. Because …

26S 蛋白酶体是一种多催化蛋白酶复合物，具有由 2 个复合物、20S 核心和 19S 调节剂组成的高度有序结构。 20S 核心由 28 个不同亚基的 4 个环组成； 2 个环由 7 个α亚基组成，2 个环由 …

Jun 19, 2023 · In this study, transcriptome sequencing of HCC tissues and non-tumor hepatic tissues from the public database Cancer Genome Atlas (TGCA) revealed a high expression of …

Jul 7, 2024 · PSMD4 regulates the malignancy of esophageal cancer cells by suppressing endoplasmic reticulum stress. Inhibition of PSMD4 blocks the tumorigenesis of hepatocellular …

Nov 5, 2021 · 在这项研究中，我们利用生化和遗传策略以及动物模型来证明靶向 ubr psmd4 会触发抗 mm 活性，包括针对 pi 抗性 mm 细胞。 材料和方法 使用 WST/CellTiter-Glo 测定和膜联 …

Nov 27, 2024 · Title: PSMD4 drives progression of hepatocellular carcinoma via Akt/COX2 pathway and p53 inhibition. Upregulation of Rpn10 promotes tumor progression via activation …

Gene/transcipt that contains an open reading frame (ORF). Protein coding. A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest …