Prospero homeobox protein 1 is a protein that in humans is encoded by the PROX1 gene. [5] [6] The Prox1 gene is critical for the development of multiple tissues. Prox1 activity is necessary …

2024年12月25日 · PROX1 (Prospero Homeobox 1) is a Protein Coding gene. Diseases associated with PROX1 include Lymphangioma and Generalized Lymphatic Anomaly. Among …

6 天之前 · In mice, Prox1 was required for efficient hepatocyte regeneration after injury and was sufficient to prevent liver tumorigenesis. In line with patient data, Prox1 depletion caused …

PROX1 is a prognostic marker in Thyroid carcinoma Cancer specificity i Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, …

PROX1 is a regulator of neuroendocrine-related gene expression in lung carcinoid. PROX1 drives neuroendocrine plasticity and liver metastases in prostate cancer. Prox1 Suppresses …

2025年1月4日 · Title: Prox1 Suppresses Proliferation and Drug Resistance of Retinoblastoma Cells via Targeting Notch1. PROX1 interaction with alpha-SMA-rich cancer-associated …

The homeobox gene Prox1, the vertebrate homologue of the Drosophila prospero gene, has been recently identified to be required for the induction of lymphatic vascular development from …

6 天之前 · To do so, PROX1 silences many factors that activate alternative cell fates thereby blocking all the other paths. In a way, looking at Waddington’s illustration of cell fate, PROX1 …

The homeobox gene PROX1 is critical for organ development during embryogenesis. The Drosophila homologue, known as prospero has been shown to act as a tumor suppressor by …

5 天之前 · The researchers demonstrated that when PROX1 levels were reduced, liver cells lost their identity, increasing their plasticity and making them more prone to tumor formation. …