Proline is the only proteinogenic amino acid which is a secondary amine, as the nitrogen atom is attached both to the α-carbon and to a chain of three carbons that together form a five-membered ring.

2018年4月1日 · Functions of proline include helping form collagen, regenerating cartilage, forming connective tissue, repairing skin damage and wounds, healing the gut lining, and repairing joints. The structure of proline is unique because it’s the only proteinogenic amino acid (the types that biosynthetically form proteins) with a secondary amine.

2023年11月23日 · Proline is particularly abundant in protein-rich foods. Here are some examples of foods that contain proline. • Meat. Proline is found in abundance in meat, including beef, chicken, pork, and lamb. • Dairy Products. Dairy foods such as milk, cheese, and yogurt contain proline. • Eggs, especially egg whites, are a good source of proline.

2010年2月1日 · Proline is a proteinogenic amino acid with an exceptional conformational rigidity, and is essential for primary metabolism. Since the first report on proline accumulation in wilting perennial rye grass (Lolium perenne) [1], numerous studies have shown that the proline content in higher plants increases under different environmental stresses.

2024年8月25日 · Proline is a unique amino acid in that its side-chain is cyclised to the backbone, thus giving proline an exceptional rigidity and a considerably restricted conformational space. Polyproline forms two well-characterized helical structures: a left-handed polyproline helix (PPII) and a right-handed polyproline helix (PPI).

Proline plays important roles in protein synthesis and structure, metabolism (particularly the synthesis of arginine, polyamines, and glutamate via pyrroline-5-carboxylate), and nutrition, as well as wound healing, antioxidative reactions, and immune responses.

2013年1月25日 · We analyzed the distribution and frequency of 687,434 proline residues among 18,666 human proteins, identifying single residues, dimers, trimers, and longer repeats. Proline accounts for 6.3% of the 10,882,808 protein amino acids. Of all proline residues, 4.4% are in trimers or longer spans.

proline, an amino acid obtained by hydrolysis of proteins. Its molecule contains a secondary amino group (>NH) rather than the primary amino group (>NH 2) characteristic of most amino acids. Unlike other amino acids, proline, first isolated from casein (1901), is readily soluble in …

Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon - nitrogen double bond. Proline is a non-essential amino acid that is synthesized from glutamic acid.

Proline is a non-essential amino acid with key roles in protein structure/function and maintenance of cellular redox homeostasis. It is available from dietary sources, generated de novo within cells, and released from protein structures; a noteworthy source being collagen.