Polo-like kinase family consists of 5 members (Plk1-Plk5) and they are involved in multiple functions in eukaryotic cell division. It regulates a variety of aspects such as, centrosome maturation, checkpoint recovery, spindle assembly, cytokinesis, apoptosis and …

The 2022–23 Polish Basketball League (PLK) season, the Energa Basket Liga for sponsorship reasons, is the 89th season of the Polish Basketball League, the highest professional basketball league in Poland. Śląsk Wrocław are the defending champions.

2024年12月25日 · PLK2 (Polo Like Kinase 2) is a Protein Coding gene. Diseases associated with PLK2 include Hereditary Breast Ovarian Cancer Syndrome and Parkinson's Disease. Among its related pathways are ADORA2B mediated anti-inflammatory cytokines production and Gene expression (Transcription).

Polo-like kinases (Plks) are regulatory serine/threonine kinases of the cell cycle involved in mitotic entry, mitotic exit, spindle formation, cytokinesis, and meiosis. [1] . Only one Plk is found in the genomes of the fly Drosophila melanogaster (Polo), budding yeast (Cdc5) and …

2014年6月23日 · Polo-like kinases (PLKs) are a family of Ser/Thr kinases that have a pivotal role in cell cycle progression, the centrosome cycle, mitosis and cellular responses...

2024年10月22日 · Polo-like kinase 2 (PLK2) is a serine/threonine protein kinase associated with the regulation of synaptic plasticity and centriole duplication. We identify PLK2 as a crucial early-response gene in lipopolysaccharide (LPS)-stimulated microglial cells.

2022年7月7日 · Polo-like kinase (PLK) 2 is an evolutionarily conserved serine/threonine kinase that shares the n-terminal kinase catalytic domain and the C-terminal Polo Box Domain (PBD) with other members of the PLKs family.

2024年5月13日 · Polo-like kinase（PLK）家族是一组丝氨酸/苏氨酸蛋白激酶，它们在细胞周期的精确调控中占据着不可或缺的地位。 特别地，PLK1在细胞周期的有丝分裂阶段扮演着至关重要的角色，并且其在多种癌细胞中的过度表达现象使其成为了重要的抗癌药物研发靶点。

2022年7月8日 · Polo-like kinase (PLK) 2 is an evolutionarily conserved serine/threonine kinase that shares the n-terminal kinase catalytic domain and the C-terminal Polo Box Domain (PBD) with other members of the PLKs family. In the last two decades, mounting studies have focused on this and tried to clarify its r …

The polo-like kinase (Plk) family is comprised of five different members (Plk1-5), each with their own distinct functions. Plk family members participate in pivotal cell division processes as well as in non-mitotic roles. Importantly, Plk expression has been correlated with various disease states, i …