2024年8月27日 · Often shows lymphocytosis with a spectrum of lymphocytes, plasmacytoid lymphocytes and plasma cells Rouleaux formation of red blood cells is routinely seen Cold agglutinin or cryoglobulin may be present Bone marrow (Arch Pathol Lab Med 2013;137:580) Involvement in almost all cases Aspirate is the most helpful sample in morphologic diagnosis

2023年9月26日 · Lymphocytes range from small to intermediate and large in size Plasma cells, plasmacytoid cells and histiocytes are variably present, less frequently accompanied by eosinophils Sinuses are regularly occupied by immunoblasts, monocytoid B cells and histiocytes Immunoblasts can be binucleated, mimicking HRS

2025年2月6日 · Small lymphocytes, plasmacytoid cells and plasma cells Small lymphocytes, monocytoid cells and plasma cells Large cells with round eccentric nucleus and prominent nucleoli Phenotype: Cytoplasmic light chain restriction; CD38+, CD138+, MUM1+, CD19-, CD56 variable, CD20-, PAX5-, cyclin D1-, MYC-, no p53 overexpression

2013年11月1日 · Found in hilar region between the sinuses, composed mostly of small B and T lymphocytes, plasmacytoid lymphocytes, plasmablasts and plasma cells. Sinuses: Carry lymph from afferent to efferent lymphatics Subcapsular sinus is below capsule and partially lined by endothelium Becomes "medullary" as it approaches the hilum and is lined by macrophages

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) (Am J Surg Pathol 2019;43:1429) Mature plasmacytoid dendritic cell proliferations (Curr Hematol Malig Rep 2018;13:477) Systemic mastocytosis (Leukemia 2016;30:914) Hairy cell leukemia (Am J Clin Pathol 2011;136:625)

4 天之前 · Papulonodular lesion show dermal, intraepithelial neoplastic lymphocytes Positive staining - normal B cells, NK cells, naive / resting T cells (those not exposed to antigens), medullary thymocytes and plasmacytoid dendritic cells ( Am J Pathol 2001;159:237 )

2022年7月27日 · Atypical lymphocytes CD10, BCL6 and BCL2 positive Clonal B cell population BCL2::IGH translocation Mantle cell lymphoma: Mantle zone pattern may mimic HVCD Atypical lymphocytes, CD5 and cyclin D1 or SOX11 positive Clonal B cell population CCND1::IGH translocation Reactive lymph node enlargement: Lack characteristic histological features of CD

3 天之前 · Blastic plasmacytoid dendritic cell neoplasm (Arch Pathol Lab Med 2007;131:149) Enteropathy associated T cell lymphoma (Am J Clin Pathol 2007;127:701, Am J Surg Pathol 2011;35:1557) Myeloid sarcoma (variable) (Am J Clin Pathol 2000;114:807) Myelofibrosis (Am J Clin Pathol 2010;133:314)

2023年5月18日 · CD38 is highly expressed on most multiple myeloma cells; the anti-CD38 monoclonal antibody daratumumab is used therapeutically in multiple myeloma patients and the response to therapy was shown to be correlated with CD38 expression as measured by flow cytometry (Br J Haematol 1999;105:441, Leukemia 2002;16:30)

6 天之前 · Peripheral B lymphocytes Plasma cells Board review style answer #1. E. Plasma cells. CD138 is a useful ...