Since the discovery two decades ago that transgenes are efficiently integrated into the genome of Physcomitrella patens by homologous recombination, this moss has been a premier model system to study evolutionary developmental biology questions, stem cell reprogramming, and the biology of non …

For studying these facets of division plane control, the moss Physcomitrium (Physcomitrella) patens has emerged as a suitable model system. Developmental progression in this organism starts out simple and transitions towards a body plan with a three-dimensional structure.

Physcomitrella is the only plant that undergoes homologous recombination with a frequency that allows easy targeting of genes for replacement and elimination, as has been crucial for the development of other model systems such as yeast, allowing gene function in …

About Physcomitrium patens. The mosses (Bryophytes) are non-vascular plants that appeared very early in the fossil record, soon after the transition of plants to terrestrial environments. The Physcomitrium patens genome is therefore valuable in understanding early evolution and adaptation of land plants.

2018年5月24日 · Physcomitrella patens accepts a variety of components of the transcription, translation and secretion machineries, originally developed and optimised for recombinant protein production in CHO cells (Gitzinger et al. 2009), revealing extra value to synthetic biologists who work with orthogonal systems.

The moss Physcomitrella patens (Funariales, Bryophyta) is being developed as a model system for plant biological studies. The dominance of the haploid gametophyte in the life cycle of this moss facilitates genetic analysis.

The moss Physcomitrella patens is an evolutionarily basal model system suitable for the analysis of plant defence responses activated after pathogen assault. Upon infection with the necrotroph Botrytis cinerea, several defence mechanisms are induced ...

The moss Physcomitrella patens, like seed plants, shows alternation of generations, but its gametophyte, the haploid phase of the life cycle, is dominant, making it ideal for genetic studies. Crosses show direct segregations, so F2 or test crosses are unnecessary.

Here, we focus on the features of mosses as versatile cell factories for synthetic biology and their impact on metabolic engineering. Keywords: Biopharmaceutical; Bioreactor; Fragrance; Gene targeting; Genome engineering; Green cell factory; Photobioreactor.

Phylogenomic delineation of Physcomitrium (Bryophyta: Funariaceae) based on targeted sequencing of nuclear exons and their flanking regions rejects the retention of Physcomitrella, Physcomitridium and Aphanorrhegma.