
PFKFB1 Gene - GeneCards | F261 Protein | F261 Antibody
2024年12月25日 · PFKFB1 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 1) is a Protein Coding gene. Diseases associated with PFKFB1 include Hepatocellular Carcinoma and Autism Spectrum Disorder. Among its related pathways are Glycolysis (REACTOME) and Integration of energy metabolism.
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase …
Results describe structural differences between two isozymes of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from liver and testis. This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes.
Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on …
PFK-2/FBPase-2 is a bifunctional enzyme responsible for F-2,6-BP synthesis and degradation. Four isozymes of PFKFB (PFKFB1, PFKFB2, PFKFB3, and PFKFB4) have been identified. Alterations in the levels of all PFK-2/FBPase-2 isozymes have been reported in different diseases.
PFKFB1 - Wikipedia
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. [5] [6] This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes.
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
2024年3月5日 · Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
2025年2月20日 · Results describe structural differences between two isozymes of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from liver and testis. Enables several functions, including 6-phosphofructo-2-kinase activity; anion binding activity; and fructose-2,6-bisphosphate 2-phosphatase activity.
Comparative clinical significance and biological roles of PFKFB …
2023年11月2日 · Phosphofructokinase-fructose bisphosphatases (PFKFBs), a family of bidirectional glycolytic enzymes, modulate the formation and degradation of fructose-2,6-bisphosphate (F-2,6-BP), thereby regulating glycolysis [7]. PFKFBs is encoded by four genes (PFKFB1, PFKFB2, PFKFB3, and PFKFB4) in humans [8].
Pfkfb (6-phosphofructo-2-kinase/fructose-2,6 ... - ScienceDirect
2013年10月1日 · Pfkfb (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) enzymes are bi-functional enzymes encoded by four different genes (pfkfb1, pfkfb2, pfkfb3, pfkfb4) in vertebrates. They are involved in the regulation of glycolysis: they catalyze the synthesis and the degradation of F-2,6-BP (fructose-2,6-bisphosphate), the most potent allosteric ...
Pfkfb1 MGI Mouse Gene Detail - MGI:107816 - 6-phosphofructo …
2024年12月10日 · View mouse Pfkfb1 ChrX:149371225-149426874 with: sequences, polymorphisms, proteins, references, function, expression
6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 1; PFKFB1 …
1998年3月2日 · The synthesis and degradation of fructose 2,6-bisphosphate are catalyzed by 6-phosphofructo-2-kinase (EC 2.7.1.105) and fructose-2,6-bisphosphatase (EC 3.1.3.46), respectively. In liver, these 2 activities belong to the same polypeptide encoded by the gene PFKFB1, which also encodes the muscle isozyme (summary by Hilliker et al., 1991).