Peptide-Based Vaccines: Current Progress and Future Challenges
2020年3月25日 · In this Review, we discuss peptide-based vaccines and their potential in three therapeutic areas: infectious disease, Alzheimer's disease, and cancer. We discuss factors that contribute to vaccine efficacy and how these parameters may potentially be modulated by design.
The Peptide Vaccine of the Future - PMC - PubMed Central (PMC)
Peptide-based vaccines represent a low-side-effect vaccination approach using synthetic tumor-associated or -specific peptides or peptide combinations that are designed to induce and activate peptide-specific tumor-reactive T cells in vivo.
Peptide-Based Vaccines: Current Progress and Future Challenges
2019年12月5日 · In this Review, we discuss peptide-based vaccines and their potential in three therapeutic areas: infectious disease, Alzheimer’s disease, and cancer. We discuss factors that contribute to vaccine efficacy and how these parameters may potentially be modulated by design.
Peptide Vaccine - an overview | ScienceDirect Topics
Peptide vaccines are based on in vitro–synthesized peptides of 20–30 amino acids, known to be highly immunogenic and to trigger the desired immune response.
Peptide vaccines - Latest research and news - Nature
2024年11月27日 · Peptide vaccines are composed of one or more microbial proteinaceous antigens that, when administered, elicit protective immunity against the microbial pathogen. The immune response to...
Peptides for Vaccine Development - PMC - PubMed Central (PMC)
This is illustrative that most peptide vaccines are in development for cancers, with a significant fraction for HIV and smaller numbers for infectious viral diseases, with the exception of COVID-19 where many trials have recently been launched due to the recent impact of the global pandemic.
More than one reason to rethink the use of peptides in vaccine …
We discuss the potential of peptide-based vaccines for the treatment of chronic viral diseases and cancer, and review recent developments in the field of peptide-based vaccines.
Peptides for Vaccine Development | ACS Applied Bio Materials
2022年2月23日 · This review discusses peptide epitopes used as antigens in the development of vaccines in clinical trials as well as future vaccine candidates. It covers peptides used in potential immunotherapies ...
The Peptide Vaccine of the Future - PubMed
In this review, current approaches in the development of peptide-based vaccines and critical implications for optimal vaccine design are discussed. Keywords: Peptide vaccine, HLA ligands, Cancer vaccination, Adjuvants, Combination therapy, Mass spectrometry, Biomarkers.
A synthetic cyclic peptide for promoting antigen presentation and ...
5 天之前 · Many adjuvants have been investigated for peptide vaccines, including particulates, oil emulsions, toll-like receptor ligands, immunostimulating complexes, and other biologically-derived materials ...
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