2020年12月11日 · PEG linkers, also known as PEG Reagents, are chemically functionalized polyethylene glycol (PEG) linkers. PEG linkers are particularly attractive as a cross-linker for conjugation and biolabeling, due to their water solubility, lack of toxicity, low immunogenicity.

Polyethylene glycol is a biologically inert, non-immunogenic chemical that confers greater water solubility to proteins, labeling tags and crosslinkers with which it is incorporated as constituent chemical group. This page provides a brief introduction to the use and types of PEG reagents available to protein biology researchers.

2024年9月24日 · PEG linkers are chemical compounds that incorporate a PEG chain to link two functional groups. These linkers are designed to facilitate the conjugation of biomolecules, drugs, or other chemical entities.

PEG linkers are widely used in pharmaceutical and biotech R&D due to their aqueous solubility and non-immunogenicity. BroadPharm has 4,000 high purity, monodispersed PEG linkers in stock for overnight shipping to empower your PEGylation, ADC …

2022年2月10日 · What Are PEG Linkers? Through a chemical synthesis reaction, PEG linkers can be made by precisely introducing functionalized groups with strong reactivity at specific molecular ends of PEG.

PEG (polyethylene glycol) linkers are essential tools in biotechnology. They connect biomolecules, improving solubility, stability, and reducing immunogenicity. Commonly used in drug delivery, bioconjugation, and diagnostics, PEG linkers come …

To investigate the chemical challenges that can be overcome by the right choice of the linker, we have explored the influence of a variety of PEG linkers on the structure of a model cysteine-bioconjugate.

PEG linkers are created by attaching PEG molecules to other molecules, such as drugs, proteins, or nanoparticles. The linkage can occur through covalent bonds, allowing for precise control over the size and properties of the PEGylated compounds.

Building blocks & intermediates for flexible linker architecture design. Chemical modification reagents with a variety sizes, architectures, and end capping. Block copolymers for polymeric and lipid nanoparticles. Affinity tags including biotin, lipids, …

PEG linkers can be used to modify the surfaces of materials, nanoparticles, or medical devices to improve their biocompatibility, reduce non-specific binding, prevent protein adsorption, and enhance stability in biological environments.