PARP14 Gene - GeneCards | PAR14 Protein | PAR14 Antibody
Dec 25, 2024 · PARP14 (Poly (ADP-Ribose) Polymerase Family Member 14) is a Protein Coding gene. Diseases associated with PARP14 include Diphtheria and Tfe3-Rearranged Renal Cell …
PARP14 inhibition restores PD-1 immune checkpoint inhibitor
Sep 26, 2023 · We observe upregulation of poly-ADP ribosyl polymerase 14 (PARP14) in chronic IFNγ-treated cancer cell models, in patient melanoma with elevated IFNG expression, and in …
PARP14 is a PARP with both ADP-ribosyl transferase and …
Sep 13, 2023 · PARP14 is a mono–ADP-ribosyl transferase involved in the control of immunity, transcription, and DNA replication stress management. However, little is known about the ADP …
【自然子刊】以Tankyrase为靶点的疗法：在PARP蛋白家族中治疗 …
parp14缺乏会延迟b细胞淋巴瘤的发生并阻止myc驱动的b细胞成熟。 PARP9，PARP14和PARP15都包含一个与ADP-核糖或聚（ADP-核糖）结合的宏结构域。 PARP12和PARP13均 …
Research Progress on PARP14 as a Drug Target - PMC
PARP14 can cleave one NAD + molecule into one ADP ribose and nicotinamide, and then transfer the mono (ADP-ribose) unit onto target proteins. Based on this particular biochemical …
Poly (adp-ribose) polymerase family member 14 - Wikipedia
Poly (ADP-ribosyl)ation is an immediate DNA damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating …
PARP14 poly(ADP-ribose) polymerase family member 14
Feb 9, 2025 · PARP14 Contributes to the Development of the Tumor-Associated Macrophage Phenotype. Targeting PARP14 with lomitapide suppresses drug resistance through the …
PARP14 is a PARP with both ADP-ribosyl transferase and
Sep 15, 2023 · We show that PARP14 is a dual-function enzyme with both ADP-ribosyl transferase and hydrolase activity acting on both protein and nucleic acid substrates. In …
PARP14 is a writer, reader, and eraser of mono-ADP-ribosylation
PARP14/BAL2 is a large multidomain enzyme involved in signaling pathways with relevance to cancer, inflammation, and infection. Inhibition of its mono-ADP-ribosylating PARP homology …
聚 (ADP-核糖) 聚合酶家族成员 14（PARP14）基因 | MCE
Ubiquitous expression in spleen (RPKM 17.4), appendix (RPKM 15.1) and 24 other tissues. 该基因编码聚 (ADP-核糖) 聚合酶 (PARP) 蛋白家族的成员。 编码的抗凋亡蛋白可以调节有氧糖酵 …