PPAR agonist - Wikipedia
PPAR agonists are drugs which act upon the peroxisome proliferator-activated receptor. They are used for the treatment of symptoms of the metabolic syndrome, mainly for lowering …
The roles of PPARγ and its agonists in autoimmune diseases: A ...
In this review, we summarize the signaling pathways and biological functions of PPARγ and focus on how PPARγ and its agonists play protective roles in autoimmune diseases, including …
Review of the Structural and Dynamic Mechanisms of PPAR
While endogenous ligands of PPAR γ include fatty acids and eicosanoids, synthetic full agonists of the receptor, including members of the thiazolidinedione (TZD) class, have been widely …
The peroxisome proliferator-activated receptor: A family of …
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of nuclear hormone receptor superfamily comprising of the following three subtypes: PPARα, …
Peroxisome proliferator-activated receptor agonists and ... - PubMed
PPARα agonists (fibrates) and PPARγ agonists (thiazolidinediones) are used for the treatment of hypertriglyceridemia and type 2 diabetes, respectively. PPARδ activation enhances …
Peroxisome proliferator-activated receptor gamma - Wikipedia
Peroxisome proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1, group …
PPARgamma in Metabolism, Immunity, and Cancer: Unified and …
2021年2月25日 · Peroxisome proliferator-activated receptor-gamma (PPAR(gamma)) inhibits tumorigenesis by reversing the undifferentiated phenotype of metastatic non-small-cell lung …
Therapeutic Roles of Peroxisome Proliferator–Activated Receptor Agonists
2005年8月1日 · Peroxisome proliferator–activated receptors (PPARs) play key roles in the regulation of energy homeostasis and inflammation, and agonists of PPARα and -γ are …
Peroxisome proliferator-activated receptor gamma and its natural ...
2022年10月20日 · Synthetic agonists of PPAR-γ were suggested to show therapeutic potential in many renal complications (Katoch et al., 2022). Anti-diabetic PPAR-γ agonist pioglitazone was …
Current Progress on Peroxisome Proliferator-activated Receptor Gamma …
Recently, both clinical and preclinical studies showed that use of Peroxisome proliferator-activated receptor gamma (PPARγ) agonist improves both learning and memory along with other AD …