
Prostaglandin D2 - Wikipedia
Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP 1), as well as CRTH2 (DP 2). [1][2] It is a major prostaglandin produced by mast cells – recruits Th2 cells, …
The prostaglandin D2 receptor 2 pathway in asthma: a key …
2018年9月29日 · The DP2 receptor pathway is a novel and important therapeutic target for asthma, because increased PGD2 production induces significant inflammatory cell chemotaxis …
Prostaglandin D2 - an overview | ScienceDirect Topics
Prostaglandin D2 (PGD2) is a major inflammatory mediator produced by mast cells and Th2 cells. PGD2 and its metabolites have been considered as selective markers of mast cell activation in …
PGD Synthase and PGD2 in Immune Resposne - PMC
PGD 2 can be either pro- or anti-inflammatory depending on disease process and etiology. The anti-inflammatory and immunomodulatory attributes of PGDS/PGD 2 provide opportunities for …
Prostaglandin D2 receptor - Wikipedia
The prostaglandin D2 (PGD2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin D 2. [1][2] Also known as PTGDR or DP receptors, they are …
Mast cell mediators: Prostaglandin D2 (PGD2)
2016年7月16日 · Prostaglandin D2 (PGD2) is the predominant prostaglandin product released by mast cells. It is found prevalently in the central nervous system and peripheral tissues, where it …
Prostaglandin D2 | C20H32O5 | CID 448457 - PubChem
It is a conjugate acid of a prostaglandin D2 (1-). The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by …
Prostaglandin D 2 receptor 2 downstream signaling and …
Increased production of Prostaglandin D 2 (PGD 2) is linked to development and progression of asthma and allergy. PGD 2 is rapidly degraded to its metabolites, which initiate type 2 innate …
Prostaglandin D2 - an overview | ScienceDirect Topics
2017年11月17日 · Prostaglandin (PG) D2 is a major PG produced in the central nervous system and is involved in the regulation of sleep and pain responses through DP receptors. It is also …
Why PGD2 has different functions from PGE2 - PubMed
Prostaglandin (PG) D 2 and PGE 2 are positional isomers; however, they sometimes exhibit opposite physiological functions, such as in cancer development. Because DP receptors are …
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