osteocyte, a cell that lies within the substance of fully formed bone. It occupies a small chamber called a lacuna, which is contained in the calcified matrix of bone. Osteocytes derive from osteoblasts, or bone-forming cells, and are essentially osteoblasts surrounded by …

2023年5月1日 · Structure. Osteocyte resides within the lacunae located between the lamellae of the matrix. Each lacuna consists of one osteocyte. Osteocytes are flat, almond-shaped in the structure; they have a depth of about 7 micrometers and length of about 15 micrometers.

Osteocytes are simply osteoblasts trapped in the matrix that they secrete. They are networked to each other via long cytoplasmic extensions that occupy tiny canals called canaliculi, which are used for exchange of nutrients and waste through gap junctions.

As the secreted matrix surrounding the osteoblast calcifies, the osteoblast become trapped within it; as a result, it changes in structure and becomes an osteocyte, the primary cell of mature bone and the most common type of bone cell.

2022年7月29日 · Osteocyte Structure. Let’s now take a look at the osteocyte structure (see bone cell diagram below). Figure 1: Diagram of bone cells. Image Credit: ResearchGate. Stellate (Star-like) shape; Osteocytes are stellate in shape. The stellate shape is due to the presence of cytoplasmic extensions (cell processes) that radiate towards the ...

2023年11月21日 · Osteocytes are cells that are located within the bone that are responsible for bone health. They are stellate shaped cells that have many processes extending from their cell body which they...

11 小时之前 · More information: Maryam Tilton et al, Tracing Cellular Senescence in Bone: Time‐Dependent Changes in Osteocyte Cytoskeleton Mechanics and Morphology, Small (2025). DOI: 10.1002/smll.202408517

Osteocytes are mechanosensor cells which regulate the behaviour of osteoblasts and osteoclasts within a specific multicellular unit (BMU), a transient anatomic structure wherein bone remodelling takes place.

In conclusion, despite the “segregation” within the mineralized bone matrix, the osteocyte is the dynamic bone cellular element that triggers/guides/modulates a series of sophisticated and interconnected processes, in hierarchic priority: their balance is allowed by osteocyte capability to sense the different bone demands (i.e., metabolic ...

Osteocytes were the forgotten bone cell until the bone community could become convinced that these cells do serve an important role in bone function and maintenance. In this review we trace the history of osteocyte characterization and present some ...