Nucleoside analogue - Wikipedia
Nucleoside analogues are structural analogues of a nucleoside, which normally contain a nucleobase and a sugar. Nucleotide analogues are analogues of a nucleotide, which normally …
Nucleoside Analogues - PubMed
The nucleoside analogues are an important class of antiviral agents now commonly used in the therapy of human immunodeficiency virus (HIV) infection, hepatitis B virus (HBV), hepatitis C …
Nucleotide and nucleoside-based drugs: past, present, and future
2022年12月1日 · Nucleotide and nucleoside-based analogue drugs are widely used for the treatment of both acute and chronic viral infections. These drugs inhibit viral replication due to …
Exploring nucleoside analogs: key targets in the viral life cycle ...
2024年5月28日 · Researchers have identified multiple nucleoside analogs exhibiting robust antiviral efficacy against SARS-CoV-2, including remdesivir, favipiravir, and molnupiravir. This …
Nucleoside Analogues - LiverTox - NCBI Bookshelf
2020年5月1日 · The nucleoside analogues resemble naturally occurring nucleosides and act by causing termination of the nascent DNA chain. These agents are generally safe and well …
Nucleoside Analogs: A Review of Its Source and Separation …
Nucleoside analogs play a crucial role in the production of high-value antitumor and antimicrobial drugs. Currently, nucleoside analogs are mainly obtained through nucleic acid degradation, …
Advances in the development of nucleoside and nucleotide analogues …
2013年5月31日 · Here, we review new nucleoside analogues and associated compounds that are currently in preclinical or clinical development for the treatment of cancer and viral infections, …
Nucleoside analogs: molecular mechanisms signaling cell death
2008年10月27日 · Nucleoside analogs are structurally similar antimetabolites that have a broad range of action and are clinically active in both solid tumors and hematological malignancies.
Discovery, Design, Synthesis, and Application of Nucleoside…
2020年3月27日 · Two of the notable papers included in this Special Issue focused on novel nucleoside scaffolds, for example, Prof. Christian Ducho’s muraymycin nucleoside analogues. …
Nucleoside analogues: mechanisms of drug resistance and …
2001年7月5日 · Nucleoside analogues (NA) are essential components of AML induction therapy (cytosine arabinoside), effective treatments of lymphoproliferative disorders (fludarabine, …