Neuregulin 4 also known as NRG4 is a member of the neuregulin protein family which in humans is encoded by the NRG4 gene. [5][6][7] The neuregulins, including NRG4, activate erb-b2 …

Nov 17, 2014 · Here we show that neuregulin 4 (Nrg4), a member of the epidermal growth factor (EGF) family of extracellular ligands, is highly expressed in adipose tissues, enriched in brown …

Dec 25, 2024 · NRG4 (Neuregulin 4) is a Protein Coding gene. Diseases associated with NRG4 include Diabetes Mellitus and Lysosomal Storage Disease. Among its related pathways are …

摘 要：神经调节蛋白4 (neuregulin 4, NRG4)是一种含有表皮生长因子(epidermal growth factor, EGF)类似区域的蛋白分子，主要 在棕色脂肪细胞中表达和分泌。 NRG4通过与EGF的受 …

NRG4是神经调节蛋白 NRG 家族成员之一，主要表达在特定的外周组织，其中以 棕色脂肪组织 表达水平最高。 NRG4 基因敲除小鼠 体重增长更快，肝内甘油三酯沉积加重，胰岛素抵抗增 …

Mar 1, 2024 · Neuregulin 4 (Nrg4), an epidermal growth factor (EGF) family member, can bind to and activate the ErbB4 receptor tyrosine kinase. Nrg4 has five different isoforms by alternative …

Sep 7, 2022 · ” 研究小组确定了一种作为疾病进展检查点的激素，它似乎具有治疗的潜力：neuregulin 4，或NRG4。 研究小组先前发现，NRG4可以保护小鼠肝脏免受NASH的影响， …

Nov 13, 2022 · Abstract: Neuregulin 4 (NRG4) is a novel fat secretion factor that is mainly expressed and secreted in brown fat. NRG4 specifically binds to epidermal growth factor …

Neuregulin 4 (Nrg4), a novel adipokine secreted mainly by brown adipose tissue (BAT), has recently been characterized as having an important effect on the regulation of energy …

Neuregulin 4 (Nrg4), a novel brown fat-enriched hormone, plays a key role in the modulation of glucose and lipid metabolism and energy balance. Recent data have demonstrated that the …