Knowing the signs of low IGF-1 levels in adults early is crucial. It helps in starting health treatments soon. This greatly helps those dealing with adult growth hormone deficiency. This …

2025年2月10日 · Receptors of insulin and insulin-like growth factors (IGFs) are receptor tyrosine kinases whose signalling controls multiple aspects of animal physiology throughout life. In...

Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in childhood growth, and has anabolic effects …

2021年10月1日 · The IGF-II receptor (cation-independent mannose-6-phosphate receptor, M6P/IGF-IIR) is a single-chain transmembrane protein that binds IGF-II and mannose-6 …

2019年12月1日 · Most studies show no increase in circulating total insulin-like growth factor (IGF)-1, whereas bioactivity of IGF-1 may change in response to exercise. GH deficiency presents …

Insulin-like growth factor I (IGF-I) is a potent hormone that stimulates growth and differentiation and inhibits apoptosis in numerous tissues. Preliminary evidence suggests that IGF-I exerts …

2016年1月6日 · In this review, we will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its clinical manifestations (impaired lipid profile, insulin resistance, …

There are eight known genetic causes of short stature characterized by low serum IGF-1 (IGF-1 deficiency, IGFD) and normal GH secretion. One of these (GHSR defect) is a form of …

本研究通过大鼠颅骨成骨细胞实验，探讨IGF-1R/NO信号通路在PEMF促进成骨细胞成熟和矿化过程中的可能作用。 SPF级SD大鼠由甘肃中医药大学动物实验中心提供 [SCXK (甘)2015-0002] …

摘要： 胰岛素样生长因子（insulin-like growth factors，IGFs）是一个多功能的生长因子家族，对细胞的生长、分化和凋亡起着重要的调节作用。 概述近年来在IGFs的成分、结构功能、信号 …