NLRP4 Gene - GeneCards | NALP4 Protein | NALP4 Antibody
Dec 25, 2024 · NLRP4 (NLR Family Pyrin Domain Containing 4) is a Protein Coding gene. Diseases associated with NLRP4 include Cinca Syndrome. Among its related pathways are …
NLRP4 - Wikipedia
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) …
NLRP4 renders pancreatic cancer resistant to olaparib through
Aug 26, 2024 · Our findings revealed that NLRP4 upregulation contributes to increased resistance to olaparib in pancreatic cancer cells, both in vitro and in vivo. RNA sequencing and Co-IP MS …
This study provides evidence that NLRP4, a constituent of the nucleotide-binding and oligomerization domain-like receptor (NLR) family, imparts resistance to olaparib in pancreatic …
Unraveling the NLRP family: Structure, function, activation, critical ...
Nov 28, 2024 · NLRP4 is a member of NLR family of cytosolic receptors and a member of an inflammation signaling cascade. Despite being important for activation of inflammatory …
NLRP4 negatively regulates type I interferon signaling by ... - Nature
Mar 4, 2012 · Here we report that the pattern-recognition receptor NLRP4 regulated the activation of type I interferon mediated by double-stranded RNA or DNA by targeting the kinase TBK1 for …
【Nature子刊】复旦大学附属肿瘤医院施思团队：NLRP4促进胰腺 …
Aug 27, 2024 · 这项研究表明，NLRP4是核苷酸结合和寡聚化结构域样受体（NLR）家族的组成部分， 在体外和体内均赋予胰腺癌细胞对奥拉帕尼的耐药性。 从机制上讲，NLRP4促进DNA修 …
NLRP4 NLR family pyrin domain containing 4 [ (human)]
Feb 8, 2025 · NLRP4 binds ARHGDIA (Rho GDP dissociation inhibitor alpha) to regulate Rho GTPase signaling and facilitate actin-mediated xenophagy. The minor allele of rs16986718G > …
NLRP4：解锁非小细胞肺癌免疫治疗新通路的关键分子 - 生物通
5 days ago · nlrp4 过表达与良好预后相关：研究人员筛选出 nlrp4 进行研究，发现 nsclc 是 nlrp4 基因组改变的第三大常见癌症类型，其突变占比达 5.89%。nlrp4 基因组突变与 mrna 水平的 …
NLRP4 unlocks an NK/macrophages-centered ecosystem to …
6 days ago · NLRP4 could trigger a distinct anti-tumor ecosystem organized by TIGIT+TNFA+ NK and iNOS+ M1 in lung cancer, discovered in TCGA analysis and verified in murine model. …