Inhaled nitric oxide in adults: Biology and indications for use
Sep 6, 2024 · Nitric oxide (NO) is a naturally occurring vasodilator produced by vascular endothelial cells. Inhaled NO is currently approved for treatment of persistent pulmonary hypertension of the newborn (PPHN).
Nitric Oxide - StatPearls - NCBI Bookshelf
Aug 28, 2023 · Off-label, it is used to treat acute bronchiolitis and as rescue therapy in patients with COVID-19 and severe ARDS after other alternatives have failed. This activity describes the indications, mechanism of action, and contraindications for nitric …
Inhaled Pulmonary Vasodilators - EMCrit Project
Aug 4, 2024 · Nitric oxide or epoprostenol are best suited for prolonged maintenance therapy because they can be precisely titrated. Most hospital units will prefer one agent (typically either nitric oxide or epoprostenol).
Nitric oxide (inhalation route) - Mayo Clinic
Jan 31, 2024 · Nitric oxide is used together with a breathing machine (ventilator) and other agents to treat newborn (term and near-term) babies with respiratory failure that is caused by pulmonary hypertension. Nitric oxide is a gas that is inhaled through the nose or mouth.
Inhaled Nitric Oxide Therapy in Adults | New England Journal ...
Dec 22, 2005 · Inhaled nitric oxide relaxes pulmonary vessels, thereby decreasing pulmonary vascular resistance, pulmonary arterial pressure, and right ventricular afterload (Table 1). 6–8 The selectivity...
Nitric Oxide in Adult Lung Disease - CHEST
Clinical studies addressing the pathophysiological role of nitric oxide in pulmonary hypertension, airway disease, and lung injury are reviewed, and the application of inhaled nitric oxide therapy is discussed.
Inhaled Nitric Oxide | Circulation - AHA/ASA Journals
Jun 29, 2004 · Extracorporeal membrane oxygenation (ECMO) therapy is lifesaving for some infants with pulmonary hypertension; however, it is costly, invasive, and associated with important morbidities.