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2024年12月25日 · NFIX (Nuclear Factor I X) is a Protein Coding gene. Diseases associated with NFIX include Malan Syndrome and Marshall-Smith Syndrome. Among its related pathways are RNA Polymerase III Transcription Initiation and Gene expression (Transcription).

Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. [5] [6] [7] NFI-X3, a splice variant of NFIX, regulates Glial fibrillary acidic protein and YKL-40 in astrocytes. [8]

2023年8月23日 · Nfix deficiency results in a loss of long-term hematopoietic stem cells and an accumulation of megakaryocyte and myelo-erythroid progenitors. NFIX interacts with PU.1 at super-enhancers to regulate gene targets involved in …

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Pathogenic variant in NFIX gene affecting three sisters due to paternal mosaicism. Excess of de novo variants in genes involved in chromatin remodelling in patients with marfanoid habitus and intellectual disability. A de-novo NFIX mutation causes …