2024年12月25日 · NDC80 (NDC80 Kinetochore Complex Component) is a Protein Coding gene. Diseases associated with NDC80 include Endometrial Adenosquamous Carcinoma and …

Ndc80 is one of the proteins of outer kinetochore.It forms a heterotetramer with proteins NUF2, SPC25, [8] and SPC24.This protein complex has microtubule-binding domains. [9]HEC is one …

1 天前 · Conversely, forces pulling Ndc80 away from the plus-end trigger mobile slip-bond behavior, facilitating sliding. This dual behavior arises from force-dependent modulation of the …

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain …

2015年9月8日 · The Ndc80 complex, which mediates end-on attachment of spindle microtubules, is linked to centromeric chromatin in human cells by two inner kinetochore proteins, CENP-T …

2006年12月31日 · Kinetochores are multicomponent assemblies that connect chromosomal centromeres to mitotic-spindle microtubules. The Ndc80 complex is an essential core element …

2020年4月27日 · Here, we summarize published data on the structure, properties, and regulation of the NDC80 complex and discuss possible relationship between changes in the expression …

The Ndc80 complex lies at the heart of the kinetochore, a large protein machine that accurately segregates chromosomes during cell division. The Ndc80 complex has structural roles in …

This review focuses on the four-subunit NDC80 complex, one of the most important kinetochore elements that plays a major role in the attachment of assembling/disassembling microtubule …

2010年10月13日 · The Ndc80 complex is a key site of regulated kinetochore–microtubule attachment (a process required for cell division), but the molecular mechanism underlying its …