MSH5 Gene - GeneCards | MSH5 Protein | MSH5 Antibody
Dec 25, 2024 · MSH5 (MutS Homolog 5) is a Protein Coding gene. Diseases associated with MSH5 include Premature Ovarian Failure 13 and Spermatogenic Failure 74. Among its related …
MSH5 - Wikipedia
MutS protein homolog 5 is a protein that in humans is encoded by the MSH5 gene. [5] [6] [7] [8]
Mutations of MSH5 in nonobstructive azoospermia (NOA) and …
Jan 3, 2022 · We found that the homozygous Msh5 mutant (p.D486Y) male mice were infertile and the size of testes was dramatically reduced, and a large number of TUNEL-positive …
同行系列 | 本周国内生殖遗传领域研究进展 No.10 - 知乎
msh5 (muts同源物5）是muts家族成员之一，已知参与dna错配修复。 在之前的研究中，研究团队在一个原发性卵巢功能不全家系中发现了msh5基因的纯合错义突变（c.1459g>t, p.d487y）。 …
4439 - Gene ResultMSH5 mutS homolog 5 [ (human)] - National …
A Homozygous Loss-of-Function Mutation in MSH5 Abolishes MutSgamma Axial Loading and Causes Meiotic Arrest in NOA-Affected Individuals. Mutations of MSH5 in nonobstructive …
Mutations in MSH5 in primary ovarian insufficiency - PubMed
Apr 15, 2017 · The homologous mutation in mice resulted in atrophic ovaries without oocytes, and in vitro functional study revealed that mutant MSH5 impaired DNA homologous recombination …
MSH5 mutS homolog 5 - NIH Genetic Testing Registry (GTR) - NCBI
Mar 5, 2024 · The human MSH5 (MutSHomolog 5) protein localizes to mitochondria and protects the mitochondrial genome from oxidative damage. hMSH5 is a nucleocytoplasmic shuttling …
Msh5 - mutS homolog 5 基因 | MCE - MCE-生物活性分子大师
This gene encodes a member of the MutS family of proteins that play critical roles in DNA mismatch repair and meiotic homologous recombination processes. Mice lacking the encoded …
The human MSH5 (MutSHomolog 5) protein localizes to
We show that MSH5 (MutSHomolog 5) is localized into the mitochondria of germ and somatic cells. This protein binds to mtDNA and interacts with the Twinkle helicase and the DNA …
The human MSH5 (MutS Homolog 5) protein localizes to …
Nov 1, 2012 · We show that MSH5 (MutS Homolog 5) is localized into the mitochondria of germ and somatic cells. This protein binds to mtDNA and interacts with the Twinkle helicase and the …