2024年5月15日 · During the first week of illness, a microscopic examination of a peripheral blood smear might reveal morulae (microcolonies of Ehrlichiae) in the cytoplasm of white blood cells. If these morulae are identified, ehrlichiosis should be strongly suspected.

In all of these cell types they occupy cytoplasmic vacuoles, usually in bacterial microcolonies known as morulae. Ehrlichia cycle in nature between ticks and mammals, and can cause disease in many mammalian species. The two known primary agents of human ehrlichiosis are E. chaffeensis and E. ewingii.

2004年2月20日 · Organisms can be identified as punctate deep-blue to gray-blue coccobacilli arranged in spherical groups, or morulae, in the cytoplasm. 8, 9, 15 By electron microscopy, the morulae have been...

Ehrlichia are small gram-negative obligately intracellular bacteria in the order Rickettsiales that are transmitted by ticks and associated with emerging life-threatening human zoonoses. Vaccines are not available for human ehrlichiosis, and ...

Clusters of Ehrlichia multiply in host monocyte vacuoles (phagosomes) to form large, mulberry-shaped aggregates called morulae. Ehrlichia inclusion bodies, such as morulae, are visible in the...

Ehrlichia parasites multiply inside host cells, forming large mulberry-shaped clusters called morulae that doctors can sometimes see on blood smears. The infection still can easily be missed. The doctor may suspect ehrlichiosis/anaplasmosis in a patient who does not respond well to treatment for Lyme disease.

Ehrlichiosis morulae is a critical diagnostic feature of ehrlichiosis, a tick-borne disease that affects both canines and humans. It refers to the presence of small clusters of ehrlichia bacteria within …

2025年3月21日 · Learn how blood smears aid in ehrlichiosis diagnosis by identifying intracellular morulae, differentiating similar infections, and assessing peripheral blood changes.

Ehrlichiosis (“err-lik-ee-OH-sis”) is an illness caused by the bacteria Ehrlichia chaffeensis, E. ewingii or E. muris eauclairensis. You can get ehrlichiosis through the bite of infected ticks, including the lone star tick and the blacklegged tick.

On light microscopy, Ehrlichia organisms form aggregates within a cytoplasmic vacuole called a morula. Morulae are large, round to oval clusters composed of small dotlike organisms, which stain as a stippled dark blue inclusion. One or more morulae may be present in a cell.