2021年4月1日 · Cerebrospinal fluid (CSF) analysis is a diagnostic tool for many conditions affecting the central nervous system. Urgent indications for lumbar puncture include suspected central nervous system...

In normal CSF, lymphocytes and monocytes are encountered. A predominance of neutrophil granulocytes suggests bacterial meningitis and prompts search for intracellular bacteria. In contrast, in viral and chronic infections lymphocytes and monocytes prevail.

The pathological findings in these group of diseases includes the presence of focal collections of lymphocytes and monocytes, with varying degrees of demyelination, axonal injury, and astroglial and microglial activation.

Monocytes in CSF are a type of white blood cell that play a key role in the immune response, particularly in phagocytosis and antigen presentation. Normally, the CSF, which bathes the central nervous system (CNS), contains a very low number of monocytes, reflecting the CNS's status as an immune-privileged site with restricted access to ...

2018年6月1日 · We assessed SF monocytes in patients presenting with microbiologically confirmed meningitis (CSF leukocyte count > 10/mm 3 for adults or > 30/mm 3 for children < 2 months), i.e. bacterial meningitis (BM), viral meningitis (VM), and neuroborreliosis (NB). Two-hundred patients (82 BM, 86 VM, and 32 NB) were included.

Objective: Cerebrospinal fluid (CSF) leukocytes analysis is commonly used to diagnose meningitis and to differentiate bacterial from viral meningitis. Interpreting CSF monocytes can be difficult for physicians, especially in France where lymphocytes and …

The maximum leukocyte count in CSF is 4 cells/1 µL with predominance of resting lymphocytes (about 70%) and a minority of resting monocytes (about 30%). The low concentration of total protein in the CSF (<430.0 mg/L) indicates normal permeability of the BCB or the absence of any disturbance in the CSF circulation.

Monocytes (%) on a CSF Cell Count Panel. Monocytes are a type of white blood cell that play an important role in the body’s immune response, primarily through phagocytosis (engulfing and digesting foreign particles, bacteria, and dead or dying cells).

Analysis of CSF is an important adjunctive diagnostic tool in the workup of patients with CNS disease and must be interpreted within the context of the patient’s history, clinical signs, clinicopathological data, imaging studies, and other ancillary diagnostics.

2018年1月1日 · In normal CSF, lymphocytes and monocytes are encountered. A predominance of neutrophil granulocytes suggests bacterial meningitis and prompts search for intracellular bacteria. In contrast, in viral and chronic infections lymphocytes and monocytes prevail. Upon activation lymphocytes typically enlarge and eventually differentiate into plasma cells.