2023年7月17日 · If you both have a mutation in the ATM gene, which is rare, there’s a chance your child could be born with a serious condition called ataxia-telangiectasia (uh-TAK-see-uh …

Monoallelic ATM pathogenic variants are also associated with an increased risk of other cancers including pancreatic and prostate cancer. Biallelic ATM pathogenic variants result in ataxia …

Recent studies have confirmed that some variants of ATM are associated with an increased risk of BC development and a worse prognosis. Thus, many patients harboring ATM mutations …

Individuals with monoallelic (heterozygous) constitutional (germline) pathogenic variants in ATM are not at risk of ataxia telangiectasia but do have an increased cancer risk, predominantly of …

People with an inherited mutation in the ATM gene have an increased risk for certain types of cancer. Read more about these cancer risks. FORCE is here to guide you.

ATM • Ataxia-telangiectasia (AT) patients (biallelic ATM mutation carriers) face an increased risk for cancer, particularly hematologic malignancies, whereas monoallelic ATM mutation carriers …

2020年7月29日 · Pathogenic germline variants in ATM are known to cause ataxia-telangiectasia, a rare hereditary syndrome notable for marked radiosensitivity. In contrast, somatic …

The inactivation of both alleles of the ATM gene leads to ataxia-telangiectasia syndrome, whereas carriers of monoallelic mutations in the ATM gene are associated with increased risk of …

2022年4月4日 · Monoallelic mutations in the ATM gene have been associated with an increased risk for developing a wide spectrum of malignancies, including cancers of the breast, stomach, …

The Medical College of Wisconsin Cancer Genetic Counseling program offers hereditary cancer gene panel testing to patients. Among those receiving panel testing, family histories of …