Mimivirus is a genus of giant viruses, in the family Mimiviridae. It is believed that Amoeba serve as their natural hosts. [2][3] It also refers to a group of phylogenetically related large viruses. [4] In colloquial speech, APMV is more commonly referred to as just "mimivirus".

The Mimivirus is a giant virus that infects amoebae and was long considered to be a bacterium due to its size. The viral particles are composed of a protein capsid of ~500 nm in diameter, which is enclosed in a polysaccharide layer in which ~120–140 ...

2017年4月1日 · The accidental discovery of the giant virus of amoeba — Acanthamoeba polyphaga mimivirus (APMV; more commonly known as mimivirus) — in 2003 changed the field of virology.

Mimiviridae is a family of viruses. Amoeba and other protists serve as natural hosts. The family contains three subfamilies that contain nine genera. [1][2][3][4] Viruses in this family belong to the nucleocytoplasmic large DNA virus clade (NCLDV), also referred to as giant viruses.

Mimivirus is the largest and most complex virus known. Is it an evolutionary bridge between nonliving viruses and living organisms, or is it just an anomaly? Viruses are small and fairly simple....

Mimivirus genome encodes five clamp loaders akin to the eukaryotic replication system. The phylogenetic analysis suggested common ancestry for mimiviral and eukaryotic DNA polymerase and its processivity factors. Mimivirus encodes three topoisomerases, namely, IA (gp243), IB (gp216), and II (gp515).

Although mimivirus was isolated in the context of a pneumonia epidemic and initially thought to be an emerging human pathogen based on positive serology, subsequent more specific PCR-based studies failed to detect mimivirus in large numbers of pneumonia patients.

2015年9月29日 · ‘Giant virus’, defined as those exhibiting viral particles easily visible by light microscopy (i.e. smallest dimension >0.3 μm), now encompass four distinct families: the Mimiviridae (with a dozen different isolates/strains) (Raoult et al. 2004; La Scola et al. 2010; Arslan et al. 2011; Colson et al. 2011b; Legendre et al. 2012; Yoosuf et al. 20...

Mimivirus is a DNA virus that infects amoebae. It is an extremely large (400 nm) particle that stains Gram-positive and has a genome size of 1.2 Mb [1]. The genome contains genes not previously reported in viruses, encoding proteins involved in translation of proteins and components of metabolic pathways [2••].

Postgenomic studies have now started in various laboratories, slowly shedding some light on the physiology of the largest and most complex virus isolated to date. This chapter summarizes our present knowledge on Mimivirus.