Milroy's disease (MD) is a familial disease characterized by lymphedema, commonly in the legs, caused by congenital abnormalities in the lymphatic system. Disruption of the normal drainage of lymph leads to fluid accumulation and hypertrophy of soft tissues.

2025年1月21日 · Milroy’s disease is a type of lymphedema that a child can inherit and have at birth. This issue makes it hard for them to manage lymphatic fluid in their legs, leading to a buildup of this fluid. Simple treatments help many children with this …

Milroy disease is a condition that affects the normal function of the lymphatic system. The lymphatic system produces and transports fluids and immune cells throughout the body. Impaired transport with accumulation of lymph fluid can cause swelling (lymphedema).

2006年4月27日 · Milroy disease is characterized by lower-limb lymphedema, present as pedal edema at (or before) birth or developing soon after. Occasionally it presents later in life. The severity of edema shows both inter- and intrafamilial variability.

Milroy disease is a genetic disorder that causes chronic lymphedema, primarily in the lower extremities. This article will cover its risk factors, symptoms, diagnostic tests, medications, procedures, and home care strategies to help manage the condition.

Milroy Disease, a rare genetic condition, primarily affects the lymphatic system and leads to chronic lymphedema. It is named after Dr. William Milroy, who first described it in the early 20th century. Milroy disease is typically present at birth or manifests within the first two years of life.

2025年1月9日 · Milroy disease is a condition that affects the normal function of the lymphatic system. The lymphatic system produces and transports fluids and immune cells throughout the body. Impaired transport with accumulation of lymph fluid can cause swelling (lymphedema).

2021年2月18日 · Clinical characteristic: Milroy disease is characterized by lower-limb lymphedema, present as pedal edema at (or before) birth or developing soon after. Occasionally it presents later in life. The severity of edema shows both inter- and intrafamilial variability. Swelling is usually bilateral but can be asymmetric.

Milroy disease is a hereditary human lymphedema condition that transmits in an autosomal dominant way, with affected patients developing edema in the lower limbs. The genetic cause lies mainly in VEGFR3 mutations, especially mutations in the tyrosine-kinase domain [24,31].

It is a familial primary congenital lymphedema disorder that involves mainly the lower limbs and is present at birth. Other clinical features include recurrent scrotal swelling, intestinal tract protein loss, persistent pulmonary pleural effusion, and hypoproteinemia.