2011年5月5日 · They love Metformin for diabetics and seem unwilling to accept muscle cramps as a side effect. Finally, saw an endocrinologist who was more willing to listen and entertain that leg cramps could be a medication side effect. She took me off Metformin temporarily. It was a miracle. Leg pains gone, no more waking up screaming in pain.

2024年6月11日 · Applies to metformin: compounding powder, oral solution, oral suspension extended release, oral tablet, oral tablet extended release. General adverse events Gastrointestinal events such as nausea, vomiting, diarrhea, abdominal pain, and loss of appetite have been frequently reported during therapy initiation and resolve spontaneously in most cases.

2013年6月21日 · The above answer has got to be the worst advice. Yes, it IS the Metformin. Leg cramping at early hours of the morning is a classic side effect. My dad has had Type II diabetes for over 15 years and has suffered from this (yours is an especially high dose, he is on 1500/day). Do NOT eat bananas if you have Type 2 diabetes.

Metformin is an FDA-approved antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, lowers liver glucose production, and improves insulin sensitivity. Metformin is recommended with dietary changes and exercise for better results.

Metformin helps to control blood sugar (glucose) levels and is sometimes used in combination with insulin or other medications. A brand name for metformin is Glumetza, but most people use the generic version these days. Metformin has been available for the oral treatment of type 2 diabetes since 1995. Why does lactic acidosis occur with Metformin?

2024年4月23日 · Postmarketing case of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. The onset is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, somnolence, and abdominal pain.

2024年2月28日 · If you have an allergy to metformin or any other part of this medicine (metformin extended-release tablets). If you are allergic to this medicine (metformin extended-release tablets); any part of this medicine (metformin extended-release tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

2024年10月2日 · Lactic acidosis can occur due to metformin accumulation during treatment with metformin / pioglitazone (immediate and extended-release formulations) and may result in death, hypothermia, hypotension, and resistant bradyarrhythmias; risk factors include renal impairment, concomitant carbonic anhydrase inhibitor use (eg, topiramate), age 65 years ...

2024年11月28日 · It is not known how metformin affects the fetus or a breastfed infant. 6. Response and effectiveness. The peak effects of metformin are seen within 2-3 hours with immediate-release forms or 4 to 8 hours with slow-release forms. May take up to 2 weeks of regular dosing for the maximum effects of metformin to develop. 7. Interactions

2024年7月29日 · Metformin: Common (1% to 10%): Hypoglycemia (5% or more when combined with glyburide) Uncommon (0.1% to 1%): Hypoglycemia; Very rare (less than 0.01%): Lactic acidosis, vitamin B12 deficiency ; In metformin-treated patients, the incidence of lactic acidosis has been about 1.5 cases per 10,000 patient years.