Antigen-specific memory T cells specific to viruses or other microbial molecules can be found in both central memory T cells (T CM) and effector memory T cells (T EM) subsets.

Memory T cells are antigen-specific T cells that remain long-term after an infection has been eliminated. The memory T cells are quickly converted into large numbers of effector T cells upon reexposure to the specific invading antigen, thus providing a rapid response to past infection.

Memory T cells pass through three distinct phases: memory generation, memory homeostasis and immunosenescence. Memory T cells are mostly generated following antigen exposure during infancy, youth and young adulthood (ages 0–20).

Immune memory, a hallmark of effective vaccination, is maintained in the T-cell compartment by subsets of Tmem cells that can give rise to protective activities, including direct effector function or generation of downstream progeny including Teff cells.

2017年12月26日 · However, a small portion of long-lived T cells still remains for rapid response upon pathogen re-exposure. This kind of cells is called memory T cells. Because memory T cells have been trained to recognize specific antigens, they will trigger a faster and stronger immune response after encountering the same antigen.

2020年10月28日 · In contrast with the classical dogma that the pathways generating either memory or ‘exhausted’ T cells are strictly segregated, data now identify a clonally distinct hybrid memory T...

Some of your T cells become memory cells instead of effector cells. Unlike effector T cells, memory T cells aren’t fighters. Instead, they remember the intruder so that if it returns, your immune system recognizes it and quickly mounts a defense.