Notice: This version of MEGA is a BETA test version that is intended to be used solely for testing purposes. Results produced using this version of MEGA should not be used for publication.

MEGA is an integrated tool for conducting automatic and manual sequence alignment, inferring phylogenetic trees, mining web-based databases, estimating rates of molecular evolution, and testing evolutionary hypotheses.

Na tively compiled graphical user interface and command-line versions of MEGA11 are available for Microsoft Windows, Linux , and macOS from www.megasoftware.net . Key words: software, phylogenetics, timetrees, tip dating, neutrality.

Help docs and user manuals for the MEGA genetics analysis software

Download previous versions of the MEGA genetics analysis software

(January 2021) MEGA11 (ALPHA) version 11.0.1 build 11210104 for Windows (macOS and Linux versions coming soon). This is an alpha test version and results obtained using this version should not be used for publication.

For MEGA11 and earlier, navigate to your ~/.config/MEGA/MEGA_buildnumber/Private folder and delete the Ini folder; In the above, the actual path to your Ini directory will depend on the version of MEGA you are using.

In any method, examining all possible topologies is very time consuming. This algorithm reduces the time spent searching by first producing a temporary tree, (e.g., an NJ tree when an ME tree is being sought), and then examining all of the topologies that are different from this temporary tree by a topological distance of dT = 2 and 4.

Molecular Evolutionary Genetics Analysis Disclaimer Although the utmost care has been taken to ensure the correctness of the software, it is provided “as is,” without any warranty of any kind.

MEGA is an integrated tool for conducting automatic and manual sequence alignment, inferring phylogenetic trees, mining web-based databases, estimating rates of molecular evolution, and testing evolutionary hypotheses.