This chapter provides an overview of mass spectrometry, focusing on ionization sources and their significance in the development of mass spectrometry in biomolecular analysis. A mass spectrometer determines the mass of a molecule by measuring the mass-to-charge ratio ( m/z ) …

Mass Spectrometry: A Historical Perspective. This timeline contains PDFs and other pages that provide deeper context to the history of Mass Spectrometry.

2018年10月17日 · Mass Spectrometry has become one of the most important tools in the biochemical sciences with capabilities ranging from small molecule analysis to protein characterization. Because of this versatility, mass spectrometry is …

Mass spectrometers accordingly must have vacuum systems and arrangements to produce, control, and vary the analyzing field(s), as well as ways to introduce samples, to create ions from the sample and get them into the analyzer, to collect analyzed ions, …

The Scripps Center for Metabolomics and Mass Spectrometry is at the forefront of developing transformative mass spectrometry-based technologies that drive progress in Biology and Chemistry.

A corona source for a liquid chromatograph-mass spec- trometer-computer analytlcal system is described. The per- formance was compared with that of the B3Ni source pre- vlously employed with direct injection of samples. Both Ion sources gave the same positive ions with solvents and test compounds.

The Siuzdak lab is credited with the creation of research tools such as eXtensible Computational Mass Spectrometry (XCMS), METLIN, METLIN Neutral Loss, and Q-MRM. Notably, the XCMS/METLIN platform hosts over 50,000 registered users.

Professor and Director Center for Metabolomics and Mass Spectrometry. Education. B.S. in Chemistry, Rhode Island College; B.A. in Mathematics, Rhode Island College; Ph.D. in Physical Chemistry, Dartmouth College; Affiliations. Honorary Doctorate - Umeå University Sweden (for contributions to metabolomics)

Mass spectrometry has revolutionized proteomics in a manner analogous to the impact of massively parallel DNA sequencing on genomics and transcriptomics. In this study, high-resolution Fourier-transform mass spectrometry was employed to systematically map the human proteome across 30 different histologically normal human tissues/cell types.

The use of electronics to revolutionize the mass doublet method of determining relative atomic masses, effectively turning mass spectrographs into mass spectrometers. The accurate measurement of the relative atomic masses of many elements using the Nier-Johnson double focusing mass spectrometer.