Mass spectrometry imaging (MSI) is a technique used in mass spectrometry to visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses. After collecting a mass spectrum at one spot, the sample is moved to reach another region, and so on, until the entire sample is scanned.

2018年2月2日 · Mass spectrometry works by ionizing chemicals in a sample and sorting the resulting ions based on their mass-to-charge ratio. An additional technique, known as mass spectrometry imaging (MSI), provides visual information about how chemical compositions are distributed spatially.

Mass spectrometry (MS) offers unmatched capabilities for the detection, characterization, and identification of a broad range of analytes. Mass spectrometry imaging (MSI) integrates MS data with information on the spatial distributions of the analytes, further enhancing the applicability of …

Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly every stage of the preclinical drug research and development (R&D) pipeline, and even to the early phase of clinical pharmaceutical evaluation.

Mass spectrometry imaging (MSI) is a powerful technology in biomedical research, made available to the Johns Hopkins research community in the Applied Imaging Mass Spectrometry (AIMS) Core.

2018年8月30日 · Matrix-assisted laser desorption/ionisation (MALDI) , desorption electrospray ionisation (DESI) , laser ablation electrospray ionisation (LAESI) and secondary ion mass spectrometry (SIMS) are the main ionisation techniques …

Mass Spectrometry Imaging (MSI) combines the capabilities of mass spectrometry with spatial resolution to map the distribution of biomolecules within tissues. It is used to analyze the localization of proteins, lipids, metabolites, and drugs, offering insights into disease mechanisms, drug efficacy, and biomarker discovery.

Mass spectrometry imaging (MSI) is technique for direct profiling of peptides, proteins, lipids and small metabolites from tissue sections. In MSI, laser ionization selectively ionizes analytes in the regions of interest on the tissue section on a pixel-by-pixel basis.

A major focus of Yost group research is the development of instrumentation and methodologies for matrix-assisted laser desorption/ionization (MALDI) mass spectrometric imaging (MSI), a microprobe technique utilized to generate chemically selective images.

This second edition details new and updated chapters on key methodologies and breakthroughs in the mass spectrometry imaging (MSI) field.