
MAP3K2 Gene - GeneCards | M3K2 Protein | M3K2 Antibody
2024年12月25日 · MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2) is a Protein Coding gene. Diseases associated with MAP3K2 include Lung Cancer and Prostate Cancer. …
MAP3K2 - Wikipedia
Mitogen-Activated Protein Kinase Kinase Kinase 2 also known as MEKK2 (MEK/ERK Kinase 2) is an enzyme that in humans is encoded by the MAP3K2 gene. [5][6][7] The protein encoded by …
Nature发表!免疫所苏冰教授课题组发现新型肠道间质细胞并揭示 …
2021年3月8日 · map3k2 是一个多器官组成性表达的丝 / 苏氨酸蛋白激酶。 在分子机制上研究人员发现 Map3k2 通过响应 DSS 诱导的损伤信号上调 R-spondin1 的表达,介导 MAPK 信号与 …
MAP3K2-regulated intestinal stromal cells define a distinct
2021年3月3日 · A subset of intestinal stromal cells that is regulated by the kinase MAP3K2 protects intestinal stem cells against injury by producing the WNT agonist R-spondin 1.
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
2014年5月21日 · Here we show that methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas. Using mouse models for …
MAP3K2 mitogen-activated protein kinase kinase kinase 2
2025年2月8日 · MEKK2 is a potent activator of the c-Jun N-terminal kinase pathway in fibroblast-like synoviocytes in rheumatoid arthritis. The protein encoded by this gene is a member of …
Functions of MAP3Ks in antiviral immunity | Immunologic …
2023年6月7日 · MAP3K2 phosphorylates IRF3 at Ser173 without involving extracellular-signal-regulated kinase 5 (ERK5) or c-Jun N-terminal kinase (JNK), increases polyubiquitination via …
丝裂原活化蛋白激酶激酶 2(MAP3K2)基因 | MCE
Ubiquitous expression in bone marrow (RPKM 11.2), thyroid (RPKM 10.3) and 25 other tissues. 该基因编码的蛋白质是丝氨酸/苏氨酸蛋白激酶家族的成员。 该激酶优先激活其他参与 MAP …
苏冰/王正廷合作揭示MAP3K2在肠道T细胞免疫中的新型调节作用
2020年7月31日 · map3k2通过il-18-jnk信号通路在肠道t细胞免疫中的新型调节作用,可为临床干预t细胞介导的肠炎提供新的潜在靶点。 图1.MAP3K2促进肠道T细胞介导的肠炎。 A .
MAP3K2-regulated intestinal stromal cells define a distinct
Here we describe a subset of intestinal stromal cells, named MAP3K2-regulated intestinal stromal cells (MRISCs), and show that they are the primary cellular source of the WNT agonist R …
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