2014年4月1日 · Import of some lipids into mitochondria occurs via the MAM. MAM regulate calcium homeostasis, mitochondrial function, autophagy and apoptosis. MAM are implicated in …

The recruitment of the preautophagosome marker ATG14L located in the MAM can trigger the formation of autophagosomes. Drp1 and ATG14L further enhance the enrichment of …

2018年2月28日 · In this review, we summarize the critical role of MAMs in initiating inflammation in the cellular defense against pathogenic infections and the association of MAMs with …

2021年6月18日 · The mitochondria-associated membrane (MAM) is a functional subdomain of the endoplasmic reticulum membrane that tethers to the mitochondrial outer membrane and is …

The interface between the endoplasmic reticulum (ER) and mitochondria referred to as the MAM (mitochondria-associated ER membrane) plays important roles in many physiological …

2013年3月3日 · Imaging data reveal that the pre-autophagosome/autophagosome marker ATG14 (also known as ATG14L) relocalizes to the ER–mitochondria contact site after starvation, and …

Our results show that GRP75-faciliated MAM formation is a potential target to overcome CP-resistance of OC. Keywords: mitochondria-associated ER membrane, glucose-regulated …

3 天之前 · This is a liquid-ordered l o-domain marker that indicates the comparatively orderly packed region within the fluid membrane nature of MAM. Mass spectrometry analysis on MAM …

Here we show that a major site of MAVS signaling is the mitochondrial-associated membrane (MAM), a distinct membrane compartment that links the endoplasmic reticulum to …

2022年5月1日 · In this view, elucidating the role of MAM in neurodegenerative diseases is particularly important. This review will focus the main tethering protein complexes of MAM and …