MECP2 (methyl CpG binding protein 2) is a gene [5] that encodes the protein MECP2. [6] MECP2 appears to be essential for the normal function of nerve cells. The protein seems to be …

MECP2 duplication syndrome is a rare neurodevelopmental condition caused by an extra copy (duplication) of the MECP2 gene. The disorder can cause a wide range of symptoms with …

2024年12月25日 · MECP2 (Methyl-CpG Binding Protein 2) is a Protein Coding gene. Diseases associated with MECP2 include Rett Syndrome and Encephalopathy, Neonatal Severe, Due …

MeCP2基因研究概况. MeCP2对哺乳动物的学习记忆能力有着重要的影响，同时也是 Rett综合症 和 MeCP2重复综合症 的致病基因。MeCP2通过多种机制对基因的转录有显著影响，而且有 …

The MECP2 gene provides instructions for making a protein called MeCP2. This protein helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein …

2024年8月20日 · Methyl-CpG-binding protein 2 (MeCP2) is an essential chromatin-binding protein whose mutations cause Rett syndrome (RTT), a severe neurological disorder that primarily...

2020年6月19日 · Our findings indicate that MeCP2 interacts with genomic loci via binding to DNA as well as histones, and that interaction between MeCP2 and histone proteins plays a key role …

近日，来自MIT的Richard A. Young课题组在Nature杂志发表了题为MeCP2 links heterochromatin condensates and neurodevelopmental disease 的文章，从 相分离 的角度阐述了MeCP2突变导 …

MECP2转录后形成MECP2-e1和MECP2-e2两种剪切体 。MECP2有3个主要的功能域：CpG结合域（methyl-CpG-bingding domain, MBD）、转录抑制域（transcription repression domain, …

MeCP2（Methyl-CpG Binding Protein 2）基因是位于X染色体上的一个重要基因，编码一种结合甲基化CpG二核苷酸的蛋白质。 这种蛋白质在调控基因表达、维持染色质结构和调控神经元功 …