2019年1月28日 · Many of these CD68 + αSMA + cells also expressed CD206, again suggesting that they had transitioned from an M2 macrophage 28,29. The evidence for MMT in two …

2025年1月27日 · The changes in M2 macrophage marker expression align with the alterations in the number of MMT cells, further confirming that M2 macrophages are the primary subsets …

2024年9月9日 · 这些研究不仅深入剖析了巨噬细胞在维持免疫稳态、调控炎症反应（如M1-M2极化平衡）以及影响血管与组织重构等关键生理病理过程中的角色，还不断拓展至新的研究领域， …

Additionally, the METTL3 inhibitor STM2457 effectively reversed M2-driven MMT and alleviated fibrotic tissue damage in CAR. These findings highlight that METTL3 enhances M2-driven …

巨噬细胞是肾脏疾病发病机制的核心，是肾损伤和纤维化的有效治疗靶点。其中，M2型巨噬细胞在抗炎作用和组织修复方面具有双刃作用。根据患病微环境中 M2 亚型（M2a 或 M2c）的极 …

2016年12月1日 · We next examined whether MMT cells exhibited an M2 phenotype based on the well-characterized M2 marker, CD206. Three-color confocal microscopy was performed in six …

2024年12月10日 · For example, in renal UUO models, 80 % of MMT cells (F4/80+α–SMA+) express CD206 according to flow cytometry results, indicating a predominance of the M2 …

2024年11月19日 · In the process of MMT, it is unclear whether epor is involved. In this study, when BMDM was induced by tgf-β1, the number of F4/80 + α-SMA + cells increased, the cells …

Additionally, the METTL3 inhibitor STM2457 effectively reversed M2‐driven MMT and alleviated fibrotic tissue damage in CAR. These findings highlight that METTL3 enhances M2‐driven …

Further analysis revealed that the CD206 + M2 macrophages co-expressed α-SMA, FSP-1 and FAP-α, suggesting that MMT cells had a predominant CD206 + M2 phenotype . In studies of …