Sep 12, 2022 · MVBs appear to be at the crossroads of multiple cellular pathways, including the endocytic pathway, the exocytosis-secretion pathway and the autophagy-lysosomal pathway …

Dec 15, 2023 · As vacuolar microautophagy, lysosomal microautophagy can degrade certain organelles and transmembrane proteins in the lysosomal membrane. Lysosomal …

During microautophagy, autophagic cargoes are directly taken up by lysosomes and late endosomes by membrane protrusion and invagination, and the autophagic cargoes are then …

Jul 1, 2024 · As vacuolar microautophagy, lysosomal microautophagy can degrade certain organelles and transmembrane proteins in the lysosomal membrane. Lysosomal …

Feb 11, 2020 · LAMP2C binds nucleic acids and potentially passes them to SIDT2 for translocation into the lysosomal lumen. d Microautophagy is the uptake of cytosolic material by …

Autophagy is a self-catabolic process through which cellular components are delivered to lysosomes for degradation. There are three types of autophagy, i.e., macroautophagy, …

Nov 21, 2023 · Here, we demonstrate that damaged lysosomal membranes are repaired by microautophagy (a process termed “microlysophagy”) and identify key regulators of the first …

Autophagy, microautophagy, and CMA are pathways to convey cytoplasmic contents to the lysosomal lumen for degradation. Additional pathways, including macropinocytosis, …

Microautophagy, the non-selective lysosomal degradative process, involves direct engulfment of cytoplasmic cargo at a boundary membrane by autophagic tubes, which mediate both …

Microautophagy involves direct lysosomal engulfment of cytoplasmic cargo without forming autophagosomes, which is essential for cell survival when cells are under stress such as …