LX-2 was generated by immmortalization of primary human hepatic stellate cells with the SV40 large T antigen followed by selective culture of early passaged cells in low serum media …

lx-2 ，人 肝星形细胞 。 肝星形细胞在慢性酒精中毒、 乙型和丙型肝炎 、 脂肪性肝病 、肥胖和糖尿病等疾病中扮演重要角色，激活后为肌成纤维细胞，是负责肝纤维化的主要细胞类型。 该 …

Recently, LX-2 cells were shown to be migratory due to increased MMP-2 activity from cytokine stimulation. 38 Increasing evidence also links matrix degradation directly to apoptosis in …

Representative fluorescent imaging of ACTA2 filaments in LX-2 cells. Cells shown stained with anti-ACTA and Alexa Fluor 488 secondary antibody. A non-treated or B treated with …

Oct 8, 2013 · The human hepatic cell line LX-2 has been described as tool to study mechanisms of hepatic fibrogenesis and the testing of antifibrotic compounds. It was originally generated by …

Hepatic stellate cells are a major cell type responsible for liver -like cells in diseases such as chronic alcoholism, hepatitis B and C, fatty liver disease, obesity and diabetes. There is an …

Human hepatic stellate cell line (LX-2) exhibits characteristics of bone marrow-derived mesenchymal stem cells. Exp. Mol. Pathol. 91:664-672(2011) PubMed=22694338; …

LX-2 cells are used to examine the cellular and molecular mechanisms underlying liver fibrosis, including the role of stellate cells in extracellular matrix deposition and the modulation of these …

Dec 1, 2011 · To detect the mesenchymal origin of LX-2 cells, we compared the expression levels of surface markers and genes related to mesenchymal stem cells, pericytes and endothelial …

Oct 25, 2018 · Note higher E-cadherin and lower Vimentin expression levels in tumour cells produced by injecting MHCC97H-shTGM2 cells and LX2 cells into nude mice, compared with …