If you have an inherited retinal disease (IRD) due to mutations in both copies of your RPE65 gene and enough remaining cells in your retina, LUXTURNA ® may help brighten up the night.. Ask your healthcare professional if LUXTURNA is right for you.

LUXTURNA is the first prescription gene therapy product to help improve functional vision in patients with an inherited retinal disease (IRD) due to a mutation in their RPE65 gene. It is a one-time gene therapy that has the potential to restore the …

Spark Therapeutics Generation Patient Services ®. If you have confirmed mutations in both copies of the RPE65 gene and have discussed treatment with your healthcare professional, you are eligible* to enroll in Spark Therapeutics Generation Patient Services.. The goal of Spark Therapeutics Generation Patient Services is to provide support that’s customized for eligible* …

Confirming mutations in both copies of the RPE65 gene is the first step to determine if you may be appropriate for treatment with LUXTURNA ®.

With the gene delivered by LUXTURNA, cells in the retina of the eye can produce the RPE65 protein. The RPE65 protein makes the visual cycle work properly.

Indication. LUXTURNA (voretigene neparvovec-rzyl) is a prescription gene therapy product used for the treatment of patients with inherited retinal disease due to mutations in both copies of the RPE65 gene, which can only be confirmed through genetic testing. You must also have enough remaining cells in your retina (the thin layer of tissue in the back of your eyes) as determined …

IMPORTANT: This Specialist Locator may provide information about healthcare professionals or links to or information about other websites not affiliated with Spark ® Therapeutics. This information is provided only as a service for convenience. Spark is not responsible for the content of such other sites and shall not be liable for any damages or injury arising from users’ access …

Dealing with an inherited retinal disease (IRD) can be difficult and navigating treatment options can be complicated. Check out the stories below to see how Spark ® Therapeutics was able to support real patients in their LUXTURNA ® treatment journey.