2024年12月25日 · LPAR2 (Lysophosphatidic Acid Receptor 2) is a Protein Coding gene. Diseases associated with LPAR2 include Ovarian Cancer and Colorectal Cancer. Among its …

LPAR1 and LPAR2 signals through G αi, G αq, and G α12/13, which trigger several downstream signaling cascades through PLC, mitogen-activated protein kinases (MAPK), protein kinase B …

LPAR2-mediated action promotes human renal cell carcinoma via MAPK/NF-kappaB signaling to regulate cytokine network. Estrogen-increased SGK1 Promotes Endometrial Stromal Cell …

2022年3月4日 · Upregulation of LPA receptor 2 (LPAR2) plays a role in carcinogenesis; however, the exact role of LPAR2 in tumors remains elusive. This study aims to explore the correlation …

LPAR1, LPAR2 and LPAR5 play essential roles in the invasion and metastasis of melanoma. Host LPA 1 and LPA 5 receptors promote B16F10 melanoma cell-derived lung metastasis. The …

LPAR2-Gi-Src-EGFR-ERK signaling cascade may mediate cell movement and LPA-stimulated COX-2 expression . Together with LPAR1, LPAR2 regulates phosphorylation of …

2022年3月4日 · Upregulation of LPA receptor 2 (LPAR2) plays a role in carcinogenesis; however, the exact role of LPAR2 in tumors remains elusive. This study aims to explore the correlation …

2023年11月23日 · LPAR2-mediated action promotes human renal cell carcinoma via MAPK/NF-κB signaling to regulate cytokine network. Wang Y, et al. J Cancer Res Clin Oncol, 2023 May. …

2023年10月10日 · In this study, we investigated whether LPAR2 signaling was implicated in the development of NSAID-induced small intestinal injury (enteropathy), another major …

We conclude that LPAR2 has a dual role in NSAID enteropathy, as it contributes to the maintenance of mucosal integrity after NSAID exposure, but also orchestrates the in …