Lipoproteins are round particles made of fat (lipids) and proteins that travel in your bloodstream to cells throughout your body. Cholesterol and triglycerides are two types of lipids found in lipoproteins.

2024年1月14日 · Lipoproteins are complex particles with a central core containing cholesterol esters and triglycerides surrounded by free cholesterol, phospholipids, and apolipoproteins, which facilitate lipoprotein formation and function.

2023年1月16日 · Lipoproteins are lipid transport molecules that transport plasma lipids. Specific lipoproteins are risk factors for cardiovascular disease and other metabolic diseases. Understanding lipoproteins and the different ways in which to manipulate their metabolism is an essential step towards preventing disease and morbidity in the general population.

2025年1月17日 · Understanding lipoproteins is essential for comprehending how our bodies manage fats and cholesterol, which has implications for cardiovascular health and disease prevention. This article explores the structure, types, and roles of lipoproteins in lipid metabolism.

Specific proteins which can reversibly and non-covalently associate with lipids, designated as lipid binding proteins or lipid chaperones, greatly enhance the aqueous solubility of lipids and facilitate their transport between tissues and within tissue cells.

2015年6月18日 · Lipids play central roles in physiology and disease, where their structural, metabolic, and signaling functions often arise from interactions with proteins. Here, we describe a set of lipid-based chemical proteomic probes and their global interaction map in mammalian cells.

Protein lipidation is a unique co-translational or posttranslational modification that plays a critical role in cell signaling, and dynamically regulates protein functions in response to extrinsic and intrinsic cues.

2019年4月12日 · In this review, we aim to provide a broad survey of MD simulations focusing on exploring lipid–protein interactions and characterizing lipid-modulated protein structure and dynamics that have been successful in providing novel insight into the mechanism of membrane protein function.

Lipid transfer proteins are critical elements in the regulation of the body’s access to lipid nutrients, to their disposition via plasma lipoprotein composition and uptake/egress into/from various cells and tissues. They are also central to the organization and composition of cellular organelles, which are bounded by lipid membranes.

2024年1月14日 · Lipoproteins are complex particles with a central core containing cholesterol esters and triglycerides surrounded by free cholesterol, phospholipids, and apolipoproteins, which facilitate lipoprotein formation and function.