Dec 25, 2024 · LIMK2 (LIM Domain Kinase 2) is a Protein Coding gene. Diseases associated with LIMK2 include Williams-Beuren Syndrome and Autism Spectrum Disorder. Among its related …

LIM domain kinase 2 is an enzyme that in humans is encoded by the LIMK2 gene. [5][6][7] There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they …

Jul 1, 2023 · LIMK2, a serine-specific kinase, was discovered as an actin dynamics regulating kinase. Emerging studies have shown its pivotal role in numerous human malignancies and …

Mar 1, 2020 · The members of the LIM kinase family of proteins (LIMK1 and 2) regulate actin dynamics by controlling the binding affinity of ADF/cofilin towards actin. LIMK2 has two major …

LIM 激酶 1 和 LIM 激酶 2 属于一个小亚家族，具有 2 个 N 末端 LIM 基序和一个 C 末端蛋白激酶结构域的独特组合。 由该基因编码的蛋白质被 Rho 的下游效应子 ROCK 磷酸化和激活，编码的 …

LIMK2 is a key regulator that acts through different substrates to provide functional links between the actin cytoskeleton and spindle dynamics. LIMK2 positively regulates the level of Aurora A, …

Mar 1, 2010 · Here, we report the identification of LIMK2, which encodes a kinase that regulates actin dynamics through phosphorylation of cofilin, as a p53 target upregulated by DNA …

LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2) are serine/threonine and tyrosine kinases and the only two members of the LIM kinase family. They play a crucial role in the regulation of …

Mar 4, 2023 · LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2) are serine/threonine and tyrosine kinases and the only two members of the LIM kinase family. They play a crucial role in the …

Jul 1, 2024 · LIMK2, a serine-specific kinase, was discovered as an actin dynamics regulating kinase. Emerging studies have shown its pivotal role in numerous human malignancies and …