双三甲基硅基胺基锂又叫六甲基二硅基氨基锂 (LiHMDS)。 双三甲基硅基胺基锂可用于制备低配位数的金属配合物，因为配体 (TMS)2N-的位阻很大。 这样的例子有M [N (TMS)2]3（M=Sc,Ti,V,Fe；TMS= (CH3)3Si)）。 与三甲基氯硅烷反应产生三 (三甲基硅基)胺，其中氮的配位数为3，空间构型为平面正三角形。 在有机合成或药物合成中，双三甲基硅基胺基 …

Lithium bis(trimethylsilyl)amide (LHMDS) is a non-nucleophilic strong base widely used in organic synthesis for deprotonation reactions and base-catalyzed reactions. It is generally soluble in most nonpolar organic solvents.

Lithium bis (trimethylsilyl)amide solution (LiHMDS) is generally used in organic synthesis as a non-nucleophilic strong Bronsted base. [1] In the deprotonation and nucleophilic difluoromethylation reactions. [2] [3] To synthesize isoquinoline derivatives by the addition of N -iodosuccinimide (NIS) to the α-benzyl tosylmethyl isocyanides. [4]

Lithium Bis (trimethylsilyl)amide (ca. 26% in Tetrahydrofuran, ca. 1.3mol/L) * Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.

2025年1月27日 · Lithium bis(trimethylsilyl)amide is used as nonnucleophilic base to generate kinetic ketone and ester enolates. It is considerably more selective than LDA and undesired reductions (e.g., of nonenolizable ketones observed in the case of LDA) can be avoided by using LHMDS. Preparation

Lithium bis (trimethylsilyl)amide is a non-nucleophilic strong Brønsted base, which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions. [1] [2] Base employed in generating enolates for the preparation of lactone precursors, [3] pyranones, [4] and cyclohexanes. [5]

Follow these links to do a live 2D search or do a live 3D search for this compound, sorted by annotation score. This section is deprecated (see here for details), but these live search links provide equivalent functionality to the table that was previously shown here. CID 13838 (Hexamethyldisilazane)

双三甲基硅基胺基锂又叫六甲基二硅基氨基锂 (LiHMDS)。 双三甲基硅基胺基锂可用于制备低配位数的金属配合物，因为配体 (TMS)2N-的位阻很大。 这样的例子有M [N (TMS)2]3（M=Sc,Ti,V,Fe；TMS= (CH3)3Si)）。 与三甲基氯硅烷反应产生三 (三甲基硅基)胺，其中氮的配位数为3，空间构型为平面正三角形。 在有机合成或药物合成中，双三甲基硅基胺基 …

Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper …

Causes severe skin burns and eye damage. Reacts violently with water. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Spot an opportunity for improvement? Share a Content Correction.