2024年12月25日 · LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor) is a Protein Coding gene. Diseases associated with LHCGR include Precocious Puberty, Male-Limited and …

The LHCGR is able to differentiate the activity of luteinizing hormone and chorionic gonadotropin. A novel point mutation of the LHCGR gene has been identified in a family affected with FMPP. …

Luteinizing hormone-choriogonadotropin receptor (LHCGR), a class A G protein-coupled receptor (GPCR), plays a pivotal role in the maturation of reproductive organs and embryonic …

LHCGR gene mutations that cause Leydig cell hypoplasia disrupt luteinizing hormone/chorionic gonadotropin receptor function, impeding the body's ability to react to these hormones. In …

2022年5月21日 · LHCGR expression predominates in ovarian tissues where it elicits functional responses through cyclic adenosine mononucleotide (cAMP), Ca 2+ and extracellular signal …

LHCGR binds luteinizing hormone (LH) as well as the highly homologous chorionic gonadotropin. Signaling from LHCGR is required for steroidogenesis and gametogenesis in males and …

The authors suggested that there is a strong founder effect in the U.S., where greater than 90% of testotoxicosis families have the asp578-to-gly mutation. Only 12 LHCGR gene mutations had …

2022年5月21日 · The human luteinising hormone choriogonadotropin receptor (LHCGR) is a G-protein coupled receptor activated by both human chorionic gonadotropin (hCG) and …

2024年12月10日 · Clinical resource with information about LHCGR, A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in …

Keywords: Function, hCG, infertility, LH, LHCGR, mutation, ovulation, polymorphism Introduction Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) serve different roles in …