LGALS9 Gene - GeneCards | LEG9 Protein | LEG9 Antibody
2024年12月25日 · LGALS9 (Galectin 9) is a Protein Coding gene. Diseases associated with LGALS9 include Dengue Virus and Echinococcosis . Among its related pathways are Cytokine …
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell ... - Nature
2021年2月5日 · Here we show that PD-1 contributes to the persistence of PD-1 + TIM-3 + T cells by binding to the TIM-3 ligand galectin-9 (Gal-9) and attenuates Gal-9/TIM-3-induced cell …
A new emerging target in cancer immunotherapy: Galectin-9 (LGALS9)
2023年11月1日 · Galectin-9 (LGALS9), a member of the galectin family, is a widely expressed protein involved in immune regulation and tumor pathogenesis, and affects the prognosis of …
Galectin-9-CD44 interaction enhances stability and function of ... - PubMed
2014年8月21日 · Galectin-9 increased iTreg cell stability and function by directly binding to its receptor CD44, which formed a complex with transforming growth factor-β (TGF-β) receptor I …
Galectin-9 suppresses B cell receptor signaling and is ... - Nature
2018年8月17日 · Functionally, we find that Gal-9 is autologously produced by naive B cells, binds CD45, suppresses calcium signaling via a Lyn-CD22-SHP-1 dependent mechanism, and …
A new emerging target in cancer immunotherapy: Galectin-9 (LGALS9)
2022年6月4日 · Galectin-9 (LGALS9), a member of the galectin family, is a widely expressed protein involved in immune regulation and tumor pathogenesis, and affects the prognosis of …
Galectin-9-CD44 Interaction Enhances Stability and Function of …
2014年8月21日 · Our data suggest that exogenous galectin-9, in addition to being an effector molecule for Treg cells, acts synergistically with TGF-β to enforce iTreg cell differentiation and …
Galectins as regulators of cell survival in the leukemia niche
2019年1月1日 · Interest in Galectin 9 (LGALS9) is growing as this galectin has been identified as an immune checkpoint molecule. LGALS9 also supports leukemia stem cells (LSCs) though a …
3965 - Gene ResultLGALS9 galectin 9 [ (human)] - National Center …
LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux TIM-3 and its ligand, galectin-9 (Gal-9), constitute …
LGALS9C Gene - GeneCards | LEG9C Protein | LEG9C Antibody
2024年12月25日 · LGALS9C (Galectin 9C) is a Protein Coding gene. Diseases associated with LGALS9C include Splenic Manifestation Of Leukemia and Amelogenesis Imperfecta, Type Ie. …
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