Lepirudin is an anticoagulant that functions as a direct thrombin inhibitor. Brand name: Refludan, Generic: Lepirudin rDNA for injection. Lepirudin is a recombinant hirudin [1] derived from yeast …

2005年6月13日 · Lepirudin is a protein-based direct thrombin inhibitor used as an anticoagulant in patients with heparin-induced thrombocytopenia.

2022年8月11日 · REFLUDAN (lepirudin) is indicated for anticoagulation in patients with heparin-induced thrombocytopenia (HIT) and associated thromboembolic disease in order to prevent …

Detailed Lepirudin dosage information for adults. Includes dosages for Thrombocytopenia Drug Induced; plus renal, liver and dialysis adjustments.

Lepirudin, a recombinant hirudin, is a direct irreversible thrombin inhibitor by binding to both free and clot-bound thrombin. It is approved for treatment of heparin-induced thrombocytopenia …

Lepirudin is a yeast cell-derived recombinant polypeptide related to the naturally occurring, leech-derived anticoagulant hirudin. Lepirudin directly binds to and inactivates thrombin, producing …

Lepirudin (Refludan), Berlex Laboratories, USA and Canada; Pharmion, all other countries), a recombinant derivative of the naturally occurring leech anticoagulant hirudin, was the first …

2024年11月8日 · Lepirudin (Refludan) generic is an anticoagulant, prescribed for heparin-induced thrombocytopenia (HIT). It blocks thrombin activity that helps to prevent the formation of blood …

2025年1月7日 · Lepirudin is used to break up clots and to reduce thrombocytopenia. It binds to thrombin and prevents thrombus or clot formation. It is a highly potent, selective, and …

[1] The first novel anticoagulant (NOAC) and direct thrombin inhibitor (DTI), lepirudin, originates from 1998, when its intravenous form was approved for the use of clinically relevant heparin …